Evidence map›Paper›PMID 35282382›Full record

ReviewFrontiers in cardiovascular medicine2022

Non-invasive Multimodality Imaging of Coronary Vulnerable Patient.

Marjorie Canu, Alexis Broisat, Laurent Riou, Gerald Vanzetto, Daniel Fagret, Catherine Ghezzi, Loic Djaileb, Gilles Barone-Rochette

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Vulnerable Atherosclerotic Plaque: Is There a Molecular Signature?International journal of molecular sciences · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marjorie CanuDepartment of Cardiology, University Hospital, Grenoble Alpes, Grenoble, France.
Alexis BroisatUniv. Grenoble Alpes, INSERM, CHU Grenoble Alpes, LRB, Grenoble, France.
Laurent RiouUniv. Grenoble Alpes, INSERM, CHU Grenoble Alpes, LRB, Grenoble, France.
Gerald VanzettoDepartment of Cardiology, University Hospital, Grenoble Alpes, Grenoble, France.
Daniel FagretUniv. Grenoble Alpes, INSERM, CHU Grenoble Alpes, LRB, Grenoble, France.
Catherine GhezziUniv. Grenoble Alpes, INSERM, CHU Grenoble Alpes, LRB, Grenoble, France.
Loic DjailebUniv. Grenoble Alpes, INSERM, CHU Grenoble Alpes, LRB, Grenoble, France.
Gilles Barone-RochetteDepartment of Cardiology, University Hospital, Grenoble Alpes, Grenoble, France.
Centre Hospitalier Universitaire de Grenoble · FRUniversité Grenoble Alpes · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerotic plaque rupture or erosion remain the primary mechanism responsible for myocardial infarction and the major challenge of cardiovascular researchers is to develop non-invasive methods of accurate risk prediction to identify vulnerable plaques before the event occurs. Multimodal imaging, by CT-TEP or CT-SPECT, provides both morphological and activity information about the plaque and cumulates the advantages of anatomic and molecular imaging to identify vulnerability features among coronary plaques. However, the rate of acute coronary syndromes remains low and the mechanisms leading to adverse events are clearly more complex than initially assumed. Indeed, recent studies suggest that the detection of a state of vulnerability in a patient is more important than the detection of individual sites of vulnerability as a target of focal treatment. Despite this evolution of concepts, multimodal imaging offers a strong potential to assess patient's vulnerability. Here we review the current state of multimodal imaging to identify vulnerable patients, and then focus on emerging imaging techniques and precision medicine.

Indexed as

chronic coronary syndromecoronary artery diseasemultimodal imagingrisk stratificationvulnerable patientvulnerable plaque

Identifiers

PMID35282382
PMCPMC8907666
OpenAlexW4213422658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.