ArticleFrontiers in cardiovascular medicine2022
Comparative Study of Diagnostic Efficacy of Single Phase-Computed Tomography Pulmonary Angiography and Dual Phase-Computed Tomography Pulmonary Angiography in the Diagnosis of Pulmonary Embolism.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Pseudo-obstruction on single-phase CTPA: unilateral pulmonary vein atresia as the cause of 50 years of hemoptysis.BMC pulmonary medicine · 2026Article
- Clinical value of the 70-kVp ultra-low-dose CT pulmonary angiography with deep learning image reconstruction.European radiology · 2026Article
- Image Findings from Dual-phase Computed Tomography Pulmonary Angiography for Diagnosing Tuberculosis-associated Fibrosing Mediastinitis.Current medical imaging · 2025Article
- Anatomic distribution of lower extremity deep venous thrombosis is associated with an increased risk of pulmonary embolism: A 10-year retrospective analysis.Frontiers in cardiovascular medicine · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
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Abstract
Objective: We compared the efficacy of single phase-computed tomography pulmonary angiography (SP-CTPA) and dual phase-computed tomography pulmonary angiography (DP-CTPA) for the diagnosis of pulmonary embolism (PE). Methods: We recruited 1,019 consecutive patients (359 with PE) who underwent DP-CTPA (phase I: pulmonary artery phase; phase II: aortic phase) for suspected PE between January and October 2021. Phase I of DP-CTPA was used as SP-CTPA, and the final clinical diagnosis (FCD) was used as the gold standard. Results: Three hundred fifty-two cases of PE were detected by both methods, with the same sensitivity of 98.1% (99.6-99.5%). Using SP-CTPA, 142 cases [13 pulmonary insufficiency artifacts (PIA) and 129 systemic-pulmonary shunt artifacts (S-PSA)] were false-positive with specificity of 78.5% (75.3-81.6%). No false-positive was found with DP-CTPA, with specificity of 100%, positive predictive value of 1, and negative predictive value of 0.990 (Net Reclassification Improvement = 0.215; Conclusion: The diagnostic efficiency of DP-CTPA for the diagnosis of PE was high. SP-CTPA may misdiagnose PIA (common in patients with PH) and S-PSA (common in patients with bronchiectasis and hemoptysis) as PE.
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