Evidence map›Paper›PMID 35282331›Full record

ArticleZoonoses (Shannon, Ireland)2021

Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria.

James R Fisher, Zachary D Chroust, Florence Onyoni, Lynn Soong

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Zoonoses (Shannon, Ireland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Differential expression ofVeterinary world · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Pathogens (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Protective effect ofFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James R FisherDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Zachary D ChroustSchool of Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Florence OnyoniGraduate School of Biomedical Sciences, University of Texas Medical Branch, Galveston, Texas, USA.
Lynn SoongDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
The University of Texas Medical Branch at Galveston · US

Funding

EMERGING AND TROPICAL INFECTIOUS DISEASEST32AI007526 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SOONG, LYNN · 1997 to 2025
$3.1M
Pathogenic Mechanisms of Vascular Dysfunction in Scrub TyphusR01AI132674 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Yuejin Liang, LYNN SOONG · 2018 to 2026
$3.0M
PREPing for SUCCESSR25GM134990 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI VARGAS, GRACIE · 2020 to 2024
$1.2M
Infectious Diseases and Inflammatory Disorders Training ProgramT35AI078878 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WANG, TIAN · 2008 to 2025
$701k
Mincle and STING Activation in Proinflammatory Responses to Orientia InfectionR21AI156536 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2021 to 2022
$435k
NIAID NIH HHS R01 AI132674NIAID NIH HHS R21 AI156536NIAID NIH HHS T32 AI007526NIAID NIH HHS T35 AI078878NIGMS NIH HHS R25 GM134990
6 · The paper itself

Abstract

Host pattern recognition receptors (PRRs) are crucial for sensing pathogenic microorganisms, launching innate responses, and shaping pathogen-specific adaptive immunity during infection.

Indexed as

AnaplasmaCoxiella burnetiiEhrlichiaInnate ImmunityObligate Intracellular BacteriaOrientia tsutsugamushiPattern Recognition ReceptorRickettsia

Identifiers

PMID35282331
PMCPMC8909792
OpenAlexW3209750851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.