ArticleJournal of orthodontic science2022
Cytotoxicity effect of orthodontic miniscrew-implant in different types of mouthwash: An in-vitro study.
Article in Journal of orthodontic science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Article
- Effects of corrosion on orthodontic mini-implants related to removal torque fracture resistance.Journal of clinical and experimental dentistry · 2025Article
- Maintaining Hygiene in Orthodontic Miniscrews: Patient Management and Protocols-A Literature Review.Dentistry journal · 2024Review
- The Orthodontic Mini-Implants Failures Based on Patient Outcomes: Systematic Review.European journal of dentistry · 2024Article
- Biocompatibility of a Ti-Rich Medium-Entropy Alloy with Glioblastoma Astrocytoma Cells.International journal of molecular sciences · 2022Article
- Effects of mouthwash exposure to stainless steel temporary anchorage device on cytotoxicity and inflammation levels of BHK-21 cells.Journal of advanced pharmaceutical technology & researchArticle
- Differences in microhardness and tensile strength of stainless steel temporary anchorage devices after exposure to fluoride, povidone-iodine, and chitosan solution.Journal of advanced pharmaceutical technology & researchArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOrthodontic miniscrew implants (OMIs) are widely used as anchorage alternatives, but recent studies revealed the corrosion behavior of OMIs when they come in contact with mouthwashes. The corrosion materials that are released can cause toxicity, allergy, and mutagenicity.
aimsThis study aims to analyze the cytotoxicity effects of OMIs exposed to different types of mouthwash using human gingival fibroblast (HGFs). SETTINGS AND
designExperimental laboratory research. METHODS AND MATERIAL: Twenty-eight samples of Ti alloy OMIs immersed separately in four groups of different types of mouthwash (chlorhexidine gluconate 0.2% mouthwash (CHX), fluoridated (sodium fluoride 0.2%) mouthwash, chitosan mouthwash 1.5%, and aquadest) for 28 d. Elution of each group and the mouthwash itself were added to the cell culture and incubated for 24 h. Changes in cell viability were performed by MTT Assay. STATISTICAL ANALYSIS USED: Data were tested for normality with Shapiro-Wilk, homogeneity with Levene test, and analyzed using an independent T-test (
resultsThe differences between the cytotoxicity of the elution of MIO and the mouthwash solution itself in the group of CHX and Fluoride were statistically significant (
conclusionsThe 1.5% chitosan mouthwash can be offered to patients with Ti alloy-based OMIs rather than the 0.2% chlorhexidine gluconate and 0.2% sodium fluoride mouthwashes.
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Registered trials
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