Evidence map›Paper›PMID 35282150›Full record

ReviewArchives of rehabilitation research and clinical translation2022

Neuromuscular Electrical Stimulation Improves Activities of Daily Living Post Stroke: A Systematic Review and Meta-analysis.

Malene Glavind Holmsted Kristensen, Henriette Busk, Troels Wienecke

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Archives of rehabilitation research and clinical translation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07282938 (Combined Effects of Soft Robotic Hand and Electrical Stimulation on Hand Function in Stroke Survivors), which is not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07282938 narecruitingnot on this mapstarted 2025, after this paper: background citation

Combined Effects of Soft Robotic Hand and Electrical Stimulation on Hand Function in Stroke Survivors

TypeinterventionalSponsorLahore University of Biological and Applied SciencesRan2025 to 2026Enrolled64ConditionsStroke, Cerebro-vascular AccidentArmsSoft Robotic Hand combined with Neuromuscular Electrical Stimulation along with Task Oriented Training, Neuromuscular Electrical Stimulation along with Task Oriented Training
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  3. High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) impacts activities of daily living of patients with post-stroke cognitive impairment: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Malene Glavind Holmsted KristensenNeurovascular Center, Department of Neurology, Zealand University Hospital, Roskilde, Denmark.
Henriette BuskNeurovascular Center, Department of Neurology, Zealand University Hospital, Roskilde, Denmark.
Troels WieneckeNeurovascular Center, Department of Neurology, Zealand University Hospital, Roskilde, Denmark.
Zealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: (1) To elucidate the effectiveness of neuromuscular electrical stimulation (NMES) toward improving activities of daily living (ADL) and functional motor ability post stroke and (2) to investigate the influence of paresis severity and the timing of treatment initiation for the effectiveness of NMES. Data Sources: PubMed, MEDLINE, Embase, Physiotherapy Evidence Database (PEDro) and Cochrane Library searched for relevant articles from database inception to May 2020. Study Selection: The inclusion criteria were randomized controlled trials exploring the effect of NMES toward improving ADL or functional motor ability in survivors of stroke. The search identified 6064 potential articles with 20 being included. Data Extraction: Two independent reviewers conducted the data extraction. Methodological quality was assessed using the PEDro scale and the Cochrane Risk of Bias Tool. Data Synthesis: Data from 428 and 659 participants (mean age, 62.4 years; 54% male) for outcomes of ADL and functional motor ability, respectively, were pooled in a random-effect meta-analysis. The analysis revealed a significant positive effect of NMES toward ADL (standardized mean difference [SMD], 0.41; 95% CI, 0.14-0.67; Conclusions: The results of the present meta-analysis are indicative of potential beneficial effects of NMES toward improving ADL post stroke, whereas the potential for improving functional motor ability appears less clear. Furthermore, subgroup analyses indicated that NMES application in the subacute stage and targeted at the upper extremity is efficacious for ADL rehabilitation and that functional motor abilities can be positively affected in patients with severe paresis.

Indexed as

ADL, activities of daily livingBRS, Brunnstrom recovery stagesCerebrovascular disordersCROB, Cochrane risk of biasElectric stimulation therapyEMG, electromyogramES, electrical stimulationFES, functional electrical stimulationMMT, manual muscle testNeurologyNIHSS, National Institutes of Health Stroke ScaleNMES, neuromuscular electrical stimulationPEDro, Physiotherapy Evidence DatabaseRehabilitationSMD, standardized mean differenceTES, therapeutic electrical stimulation

Identifiers

PMID35282150
PMCPMC8904887
OpenAlexW3211717018

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.