Evidence map›Paper›PMID 35282004›Full record

ArticleFood science & nutrition2022

New associations of serum β-carotene, lycopene, and zeaxanthin concentrations with

Ingrida Domarkienė, Asta Mažeikienė, Guostė Petrauskaitė, Zita Aušrelė Kučinskienė, Vaidutis Kučinskas

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ingrida DomarkienėDepartment of Human and Medical Genetics Faculty of Medicine Institute of Biomedical Sciences Vilnius University Vilnius Lithuania.ORCID https://orcid.org/0000-0002-2088-8620
Asta MažeikienėDepartment of Physiology Biochemistry, Microbiology and Laboratory Medicine Faculty of Medicine Institute of Biomedical Sciences Vilnius University Vilnius Lithuania.
Guostė PetrauskaitėDepartment of Human and Medical Genetics Faculty of Medicine Institute of Biomedical Sciences Vilnius University Vilnius Lithuania.
Zita Aušrelė KučinskienėDepartment of Physiology Biochemistry, Microbiology and Laboratory Medicine Faculty of Medicine Institute of Biomedical Sciences Vilnius University Vilnius Lithuania.
Vaidutis KučinskasDepartment of Human and Medical Genetics Faculty of Medicine Institute of Biomedical Sciences Vilnius University Vilnius Lithuania.
Vilnius University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Variation in carotenoid bioavailability at individual and population levels might depend on host-related factors where genetic variation has a part to play. It manifests itself through the proteins involved in carotenoid intestinal absorption and metabolism, blood lipoprotein transport, or tissue uptake. This study aims to identify novel SNPs which could be associated with carotenoid serum concentrations. A total of 265 self-reported healthy individuals of Lithuanian origin were genotyped (Illumina HumanOmniExpress-12v1.0 or v1.1 and Infinium OmniExpress-24v1.2 arrays) and fasting blood serum concentrations of β- and α-carotene, β-cryptoxanthin, lycopene, lutein, and zeaxanthin were measured (Shimadzu Prominence HPLC system). According to the individual carotenoid concentrations, the cohort was subdivided into quartiles. Q1 and Q4 were used for the following association analysis. The set of 2883 SNPs in 109 potential candidate genes (assumed for a direct or indirect role in carotenoid bioavailability) was analyzed. Liver X receptor alpha (

Indexed as

association analysisbioavailabilitycarotenoid concentrationgenetic variationsingle‐nucleotide polymorphisms (SNPs)

Identifiers

PMID35282004
PMCPMC8907718
OpenAlexW4205322703

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.