Evidence map›Paper›PMID 35281950›Full record

Trial reportComputational and mathematical methods in medicine2022

Effect Evaluation of Platelet-Rich Plasma Combined with Vacuum Sealing Drainage on Serum Inflammatory Factors in Patients with Pressure Ulcer by Intelligent Algorithm-Based CT Image.

Jingzhe Yang, Changshuan Xiao, Hailing Wen, Kui Sun, Xiaoming Wu, Xinshu Feng

RetractedOpen access · hybridAbstract readRandomized Controlled TrialRetracted Publication
In one paragraph

Trial report in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparison of Leukocyte-Rich and Leukocyte-Poor Platelet-Rich Plasma on Pressure Ulcer in a Rat Model.Journal of burn care & research : official publication of the American Burn Association · 2023
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jingzhe YangDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0002-2683-4922
Changshuan XiaoDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0001-5458-9613
Hailing WenDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0003-3604-7583
Kui SunDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0002-3329-1217
Xiaoming WuDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0001-9552-5069
Xinshu FengDepartment of Burn and Plastic Surgery, Affiliated Hospital of Chengde Medical University, Chengde, 067000 Hebei, China.ORCID https://orcid.org/0000-0002-3445-6511
Chengde Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work was to explore the efficacy of intelligent algorithm-based computed tomography (CT) to evaluate platelet-rich plasma (PRP) combined with vacuum sealing drainage (VSD) in the treatment of patients with pressure ulcers. Based on the u-net network structure, an image denoising algorithm based on double residual convolution neural network (Dr-CNN) was proposed to denoise the CT images. A total of 84 patients who were hospitalized in hospital were randomly divided into group A (without any intervention), group B (PRP treatment), group C (VSD treatment), and group D (PRP+VSD treatment). Procalcitonin (PCT) was detected by enzyme-linked immunosorbent assay (ELISA) combined with immunofluorescence method, C-reactive protein (CRP) was detected by rate reflectance turbidimetry (RRT), and interleukin-6 (IL-6) was detected by electrochemiluminescence method. The results showed that after treatment, 44 cases (52.38%) of pressure ulcers patients recovered, 24 cases (28.57%) had no change in stage, and 16 cases (19.04%) developed pressure ulcers. The pain scores of group D at 1 week (3.35 ± 0.56 points) and 2 weeks (2.76 ± 0.55 points) after treatment were significantly lower than those in group C (7.77 ± 0.58 points and 6.34 ± 0.44 points, respectively). The time of complete wound healing in group D (24.5 ± 2.32) was obviously lower in contrast to that in groups A, B, and C (35.54 ± 3.22 days, 30.23 ± 2 days, and 29.34 ± 2.15 days, respectively). In addition, the medical satisfaction of group D (8.74 ± 0.69) was significantly higher than that of groups A, B, and C (4.69 ± 0.85, 5.22 ± 0.31, and 5.18 ± 0.59, respectively). The levels of IL-6 and PCT in group D were lower than those in groups A, B, and C, and the differences were statistically significant (

Indexed as

AlgorithmsAdultAgedCombined Modality TherapyComputational BiologyDeep LearningFemaleHumansInflammation MediatorsMaleMiddle AgedNegative-Pressure Wound TherapyNeural Networks, ComputerPlatelet-Rich PlasmaPressure UlcerSignal-To-Noise RatioInflammation Mediators

Identifiers

PMID35281950
PMCPMC8906978
OpenAlexW4214935235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.