Evidence map›Paper›PMID 35281894›Full record

ReviewFrontiers in pharmacology2022

Chinese Medicinal Herb-Derived Carbon Dots for Common Diseases: Efficacies and Potential Mechanisms.

Dan Li, Kun-Yan Xu, Wei-Peng Zhao, Ming-Feng Liu, Rui Feng, De-Qiang Li, Jing Bai, Wen-Li Du

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Evaluation ofInternational journal of nanomedicine · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Carbon dots derived fromFrontiers in molecular biosciences · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dan LiDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Kun-Yan XuDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Wei-Peng ZhaoDepartment of Traditional Chinese Medicine, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Ming-Feng LiuDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Rui FengDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
De-Qiang LiDepartment of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Jing BaiDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Wen-Li DuDepartment of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNFourth Hospital of Hebei Medical University · CNSecond Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of hemorrhagic diseases and other commonly refractory diseases (including gout, inflammatory diseases, cancer, pain of various forms and causes) are very challenging in clinical practice. Charcoal medicine is a frequently used complementary and alternative drug therapy for hemorrhagic diseases. However, studies (other than those assessing effects on hemostasis) on charcoal-processed medicines are limited. Carbon dots (CDs) are quasi-spherical nanoparticles that are biocompatible and have high stability, low toxicity, unique optical properties. Currently, there are various studies carried out to evaluate their efficacy and safety. The exploration of using traditional Chinese medicine (TCM) -based CDs for the treatment of common diseases has received great attention. This review summarizes the literatures on medicinal herbs-derived CDs for the treatment of the difficult-to-treat diseases, and explored the possible mechanisms involved in the process of treatment.

Indexed as

cancercarbon dots (CDs)gouthemorrhagic diseasesinflammatory diseasespaintraditional chinese medicines (TCM)

Identifiers

PMID35281894
PMCPMC8906921
OpenAlexW4213030053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.