Evidence map›Paper›PMID 35281785›Full record

ArticleMedComm2022

SARS-CoV-2 triggered oxidative stress and abnormal energy metabolism in gut microbiota.

Tuoyu Zhou, Jingyuan Wu, Yufei Zeng, Junfeng Li, Jun Yan, Wenbo Meng, Huawen Han, Fengya Feng, Jufang He, Shuai Zhao and 8 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. The metaproteome of the gut microbiota in pediatric patients affected by COVID-19.Frontiers in cellular and infection microbiology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Tuoyu ZhouMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Jingyuan WuGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Yufei ZengState Key Joint Laboratory of Environment Simulation and Pollution Control School of Environment Tsinghua University Beijing P. R. China.
Junfeng LiGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Jun YanGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Wenbo MengGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Huawen HanMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Fengya FengMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Jufang HeGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Shuai ZhaoMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Ping ZhouGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Ying WuMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Yanlin YangGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Rong HanMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.
Weilin JinMedical Frontier Innovation Research Center The First Hospital of Lanzhou University Lanzhou P. R. China.
Xun LiGansu Province Key Laboratory Biotherapy and Regenerative Medicine The First Hospital of Lanzhou University Lanzhou P. R. China.
Yunfeng YangState Key Joint Laboratory of Environment Simulation and Pollution Control School of Environment Tsinghua University Beijing P. R. China.
Xiangkai LiMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou P. R. China.ORCID https://orcid.org/0000-0003-2931-7565
First Hospital of Lanzhou University · CNState Key Joint Laboratory of Environment Simulation and Pollution Control · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific roles of gut microbes in COVID-19 progression are critical. However, the circumstantial mechanism remains elusive. In this study, shotgun metagenomic or metatranscriptomic sequencing was performed on fecal samples collected from 13 COVID-19 patients and controls. We analyzed the structure of gut microbiota, identified the characteristic bacteria, and selected biomarkers. Further, gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations were employed to correlate the taxon alterations and corresponding functions. The gut microbiota of COVID-19 patients was characterized by the enrichment of opportunistic pathogens and depletion of commensals. The abundance of

Indexed as

COVID‐19gut microbiotametagenomemetatranscriptomeSARS‐CoV‐2

Identifiers

PMID35281785
PMCPMC8906553
OpenAlexW4206403185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.