Evidence map›Paper›PMID 35281705›Full record

ArticleOpen forum infectious diseases2022

Long-term Prognosis Following Vascular Graft Infection: A 10-Year Cohort Study.

Thibault Sixt, Serge Aho, Pascal Chavanet, Florian Moretto, Eric Denes, Sophie Mahy, Mathieu Blot, François-Xavier Catherine, Eric Steinmetz, Lionel Piroth

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Reinfection incidence following surgical intervention for infected aortic bypass: a meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Fluoroquinolones and Biofilm: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Medicina (Kaunas, Lithuania) · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Thibault SixtInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.ORCID https://orcid.org/0000-0002-2966-6346
Serge AhoHospital Epidemiology and Infection Control Department, Dijon-Bourgogne University Hospital, Dijon, France.
Pascal ChavanetInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.
Florian MorettoInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.
Eric DenesInfectious Diseases Department, Polyclinique de Limoges, Limoges, France.
Sophie MahyInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.
Mathieu BlotInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.
François-Xavier CatherineInfectious Diseases Department, Chalon sur Saône Hospital, Chalon sur Saône, France.
Eric SteinmetzCardiovascular and Thoracic Surgery Department, Dijon-Bourgogne University Hospital, Dijon, France.
Lionel PirothInfectious Diseases Department, Dijon-Bourgogne University Hospital, Dijon, France.
CHU Dijon Bourgogne · FRInserm · FRCentre Hospitalier Universitaire Henri-Mondor · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vascular graft infection (VGI) remains a severe disease with high mortality and relapse rates. We performed a retrospective single-center cohort study to highlight factors associated with long-term all-cause mortality in patients with vascular graft infection. Methods: All patients hospitalized in our facility over 10 years for VGI were included. VGI was defined by the presence of a vascular graft or an aortic stent graft (stent or fabric), associated with 2 criteria among clinical, biological, imaging, or microbiological elements in favor of VGI. The primary outcome was all-cause mortality. Empirical antibiotic therapy was considered as appropriate when all involved pathogens were susceptible in vitro to the antibiotics used. The surgical strategy was defined as nonoptimal when the graft was not removed in a late-onset surgery (>3 months) or no surgery was performed. Results: One hundred forty-six patients were included. Empirical antibiotic therapy was administered in 98 (67%) patients and considered appropriate in 55 (56%) patients. Surgery was performed in 136 patients (96%) and considered as optimal in 106 (73%) patients. In multivariable analysis, appropriate empirical antibiotic therapy was associated with a lower probability of mortality (hazard ratio, 0.47 [95% confidence interval, .30-.79]; Conclusions: Appropriate empirical antibiotic therapy is a cornerstone of the management of VGI. Whenever possible, antibiotics must be associated with optimal surgical management. However, surgery could potentially be avoided in comorbid patients who are treated with appropriate antibiotics.

Indexed as

appropriate empirical antibiotic therapyfluoroquinolonelong-term prognosisoptimal infectious surgical strategyvascular graft infection

Identifiers

PMID35281705
PMCPMC8907415
OpenAlexW4210726294

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.