Evidence map›Paper›PMID 35281669›Full record

ArticleGene reports2022

Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units.

Zahra Rafat, Alireza Ramandi, Pegah Afarinesh Khaki, Saham Ansari, Sara Ghaderkhani, Hassan Haidar, Faezeh Tajari, Davoud Roostaei, Roshanak Daei Ghazvini, Seyed Jamal Hashemi and 2 more

Open access · greenAbstract read
In one paragraph

Article in Gene reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Pulmonary mucormycosis andAnnals of medicine and surgery (2012) · 2025
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  9. Co-Infection of SARS-CoV-2 andDiagnostics (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Review
  12. Candida-bacterial cross-kingdom interactions.Trends in microbiology · 2023
    Review
  13. Article
  14. Respiratory viruses: their importance and lessons learned from COVID-19.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  15. Article
  16. Mycetoma due toIDCases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Zahra RafatDepartment of Medical Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Alireza RamandiDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Pegah Afarinesh KhakiDepartment of Molecular Genetics, Faculty of Advanced Science and Technology, Islamic Azad University, Tehran, Iran.
Saham AnsariDepartment of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sara GhaderkhaniDepartment of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Hassan HaidarSchool of Medicine, Marmara University, Istanbul, Turkey.
Faezeh TajariStudents' Scientific Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Davoud RoostaeiDepartment of Pharmacology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Roshanak Daei GhazviniDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Jamal HashemiDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Alireza AbdollahiDepartment of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences Tehran, Iran.
Hasti Kamali SarvestaniDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRGuilan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRImam Khomeini Hospital · IRIslamic Azad University, Tehran · IRMarmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: The pandemic of COVID-19 has created a global public health crisis. ICU patients with COVID-19 are prone to infections of bacterial and/or fungal origins due to several risk factors. Consequently, the current study was conducted to evaluate the frequency, demographic characteristics, underlying conditions, and etiologic agents of fungal and bacterial co-infections of the respiratory tract among ICU patients with COVID-19 in Iran. Materials and methods: From May to October 2020, sputa and endotracheal aspirates were collected from ICU patients hospitalized with COVID-19 who also were suspected of bacterial and/or fungal co-infections according to inclusion criteria. The etiologic agents of bacterial co-infections were identified using the Vitek 2 identification method. For fungal identification, all samples were analyzed by direct microscopy using KOH 10% and culture. Furthermore, all isolates were subjected to sequencing method. Results: A total of 73 lung specimens were obtained from patients who met the inclusion criteria. Of these, in 15 cases (20.54%) fungal and/or bacterial co-infections were confirmed. Males were more infected (73.33%) and all of them were between 49 and 79 years. Conclusion: The frequency of bacterial co-infections of the respiratory tract in ICU patients hospitalized with COVID-19 was relatively high. According to the results, one of the causes of death of these patients could be a secondary infection.

Indexed as

Bacterial infectionsBHI, Brain Heart InfusionCoinfectionCOVID-19COVID-19, coronavirus disease 2019Fungal infectionIranRespiratory tractSARS-CoV-2, Severe Acute Respiratory Coronavirus 2SDA, Sabouraud Dextrose Agar

Identifiers

PMID35281669
PMCPMC8902060
OpenAlexW4220825230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.