Evidence map›Paper›PMID 35281594›Full record

ArticleBioMed research international2022

Human Umbilical Cord Mesenchymal Stem Cells Prevent Bacterial Biofilm Formation.

Haoming Yang, Fang Xu, Xuaner Zheng, Shumei Yang, Zhuxiao Ren, Jie Yang

Abstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haoming YangGuangdong Women and Children Hospital, Guangzhou, China.ORCID https://orcid.org/0000-0001-6890-8064
Fang XuGuangdong Women and Children Hospital, Guangzhou, China.
Xuaner ZhengGuangdong Women and Children Hospital, Guangzhou, China.ORCID https://orcid.org/0000-0003-0675-1561
Shumei YangGuangdong Women and Children Hospital, Guangzhou, China.ORCID https://orcid.org/0000-0002-6015-1770
Zhuxiao RenGuangdong Women and Children Hospital, Guangzhou, China.
Jie YangGuangdong Women and Children Hospital, Guangzhou, China.ORCID https://orcid.org/0000-0002-7691-0241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm formation is easily found in patients suffered from ventilator-associated pneumonia (VAP) in neonatal intensive care unit (NICU) and makes the VAP infections not only harder to be treated but easier to relapse. In order to find some novel ways to inhibit biofilm formation, this study describe a previously unrecognized role for the human umbilical cord mesenchymal stem cells (hUCMSCs). In addition to multiple differentiation, hUCMSCs have the ability to prevent the biofilms formation in vitro by secreting antibacterial peptides (LL-37 and hBD-2). This occurred while

Indexed as

Mesenchymal Stem CellsUmbilical CordAnti-Bacterial AgentsBiofilmsHumansInfant, NewbornInfant, PrematureAnti-Bacterial Agents

Identifiers

PMID35281594
PMCPMC8913149

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.