Evidence map›Paper›PMID 35281587›Full record

SynthesisJournal of interventional cardiology2022

Sex-Specific Difference in Outcomes after Transcatheter Mitral Valve Repair with MitraClip Implantation: A Systematic Review and Meta-Analysis.

Fuqiang Sun, Honghao Liu, Qi Zhang, Jiawei Zhou, Haibo Zhan, Fanfan Lu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of interventional cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Transcatheter mitral and tricuspid therapy: outcomes in female patients.Indian journal of thoracic and cardiovascular surgery · 2026
    Review
  2. Article
  3. Inpatient Outcomes of Tricuspid Transcatheter Edge-to-Edge Repair in the United States Based on Sex.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fuqiang SunDepartment of Cardiovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0001-7130-3218
Honghao LiuDepartment of Emergency, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qi ZhangDepartment of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jiawei ZhouDepartment of Cardiovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Haibo ZhanDepartment of Cardiovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fanfan LuDepartment of Cardiovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Implantation of the MitraClip is a safe and effective therapy for mitral valve repair in patients ineligible for surgery or at high risk of adverse surgical outcomes. However, only limited information is available concerning sex differences in transcatheter mitral valve repair. We therefore sought to conduct a comprehensive meta-analysis of studies that investigated differences between men and women in outcomes following MitraClip implantation. Methods: The PubMed and Embase databases were searched until November 2019 for studies reporting outcomes after MitraClip implantation in women versus men. Outcomes included all-cause mortality and major complications at 30 days and one year of follow-up. Results: Six studies ( Conclusion: Gender disparity was not found in complications or prognosis of patients undergoing MitraClip implantation. This study suggests that gender should not be considered as a critical factor in the selection of patients as candidates for MitraClip implantation of concern during follow-up.

Indexed as

Heart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyCardiac CatheterizationFemaleHeart Valve ProsthesisHumansMaleSex FactorsTreatment Outcome

Identifiers

PMID35281587
PMCPMC8885186
OpenAlexW4213331783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.