Evidence map›Paper›PMID 35281414›Full record

ArticleTranslational cancer research2022

Analysis of prognostic and therapeutic values of drug resistance-related genes in the lung cancer microenvironment.

Liang Zhu, Peixin Chen, Hao Wang, Lishu Zhao, Haoyue Guo, Minlin Jiang, Sha Zhao, Wei Li, Jun Zhu, Jia Yu and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Liang Zhu *School of Medicine, Tongji University, Shanghai, China.
Peixin Chen *School of Medicine, Tongji University, Shanghai, China.
Hao WangSchool of Medicine, Tongji University, Shanghai, China.
Lishu ZhaoSchool of Medicine, Tongji University, Shanghai, China.
Haoyue GuoSchool of Medicine, Tongji University, Shanghai, China.
Minlin JiangSchool of Medicine, Tongji University, Shanghai, China.
Sha ZhaoSchool of Medicine, Tongji University, Shanghai, China.
Wei LiSchool of Medicine, Tongji University, Shanghai, China.
Jun ZhuSchool of Medicine, Tongji University, Shanghai, China.
Jia YuSchool of Medicine, Tongji University, Shanghai, China.
Jiawei DaiSJTU-Yale Joint Center for Biostatistics and Data Science, Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Tongji University · CNShanghai Pulmonary Hospital · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The interaction between cancer cells and stromal cells has a significant contribution in tumorigenesis and tumor development, and plays an anti-tumor immune effect under the regulation of drug resistance-related genes, which affects the outcome of patients. Coiled-coil domain-containing protein 73 ( Methods: ONCOMINE, GEPIA, UALCAN, cBioPortal, GeneMANIA, STRING, and TIMER were utilized in this study. Results: The transcriptional expression level of Conclusions: Novel screening for immunotherapy targets and prognostic biomarkers in lung cancer may draw inspiration from our results.

Indexed as

bioinformatics analysisbiomarkersLung cancerprognosistumor microenvironment

Identifiers

PMID35281414
PMCPMC8904958
OpenAlexW4221105308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.