ArticleAnesthesia, essays and researches
A Prospective Observational Study of Plethysmograph Variability Index and Perfusion Index in Predicting Hypotension with Propofol Induction in Noncardiac Surgeries.
Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Preoperative patient risk factors for intraoperative hypotension: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Hemodynamic changes in the prone position according to fluid loading after anaesthesia induction in patients undergoing lumbar spine surgery: a randomized, assessor-blind, prospective study.Annals of medicine · 2024Trial
- The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: Propofol induction is associated with hypotension due to changes in intravascular volume, tone of vessels and cardiac output. Plethysmograph variability index (PVI) and perfusion index (PI) are derived indices from pulse oximeter, used for assessing fluid responsiveness and vessel tone, respectively. We studied the utility of these indices in predicting hypotension due to propofol. Aims: The aim of the study is to test the baseline cutoff values of PVI > 15% and PI <1.05 in predicting hypotension with propofol induction. Settings and Design: This is a prospective double-blind observational study in tertiary care hospital. Methods: Institutional ethical committee approval was obtained. 106 surgical in-patients as per inclusion and exclusion criteria were randomly allotted by computer-generated random numbers. All patients were nil by mouth for 6 h. Injection midazolam and fentanyl were used as premedicants. Propofol at dose of 2 mg.kg Statistical Analysis: Data were analyzed with SPSS version 20. Quantitative data were analyzed using mean, standard deviation, interquartile range as per distribution. Shapiro-Wilk test with Results: Eighty-one patients (76.4%) who had hypotension were grouped into Group H and 25 patients (23.6%) without hypotension as Group NH. There was no difference between groups with respect to doses of midazolam ( Conclusion: Baseline values of PVI >15% and PI < 1.05 are not good tools for predicting hypotension with propofol induction. New values of baseline cutoff of PVI >17.5% have high specificity, and PI > 0.76 has high sensitivity and positive predictive value.
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