Evidence map›Paper›PMID 35281333›Full record

SynthesisDevelopment and psychopathology2021

The Transdiagnostic Origins of Anxiety and Depression During the Pediatric Period: Linking NIMH Research Domain Criteria (RDoC) Constructs to Ecological Systems.

Jenalee R Doom, Michelle Rozenman, Kathryn R Fox, Tiffany Phu, Anni R Subar, Deborah Seok, Kenia M Rivera

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Development and psychopathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Research Domain Criteria (RDoC) and Youth Depression - In Context.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jenalee R Doom
Michelle Rozenman
Kathryn R Fox
Tiffany Phu
Anni R Subar
Deborah Seok
Kenia M RiveraDepartment of Psychology, University of Denver.

Funding

Reducing Fetal Exposure to Maternal Depression to Improve Infant Risk MechanismsR01MH109662 · NIMH · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DAVIS, ELYSIA POGGI, HANKIN, BENJAMIN L · 2017 to 2021
$4.0M
Video-visit behavior therapy for anxiety and depression in youth: A randomized effectiveness-implementation study in low-resource primary care settings.R56MH125159 · NIMH · SAN DIEGO STATE UNIVERSITY · PI LYNCH, FRANCES L, WEERSING, V ROBIN · 2020 to 2021
$789k
Testing cortisol dysregulation as a mediator between early stress and adolescent cardiovascular healthK01HL143159 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DOOM, JENALEE RAE · 2019 to 2023
$788k
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric AnxietyR61MH121552 · NIMH · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI ROZENMAN, MICHELLE SHERRY · 2020 to 2021
$404k
NHLBI NIH HHS K01 HL143159NIMH NIH HHS R01 MH109662NIMH NIH HHS R56 MH125159NIMH NIH HHS R61 MH121552
6 · The paper itself

Abstract

In the last decade, an abundance of research has utilized the NIMH Research Domain Criteria (RDoC) framework to examine mechanisms underlying anxiety and depression in youth. However, relatively little work has examined how these mechanistic intrapersonal processes intersect with context during childhood and adolescence. The current paper covers reviews and meta-analyses that have linked RDoC-relevant constructs to ecological systems in internalizing problems in youth. Specifically, cognitive, biological, and affective factors within the RDoC framework were examined. Based on these reviews and some of the original empirical research they cover, we highlight the integral role of ecological factors to the RDoC framework in predicting onset and maintenance of internalizing problems in youth. Specific recommendations are provided for researchers using the RDoC framework to inform future research integrating ecological systems and development. We advocate for future research and research funding to focus on better integration of the environment and development into the RDoC framework.

Indexed as

AnxietyDepressionAdolescentAnxiety DisordersChildEcosystemHumansNational Institute of Mental Health (U.S.)United Statesanxietydepressionecological systems theoryRDoCyouth

Identifiers

PMID35281333
PMCPMC8916713

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.