Evidence map›Paper›PMID 35281273›Full record

ArticleFrontiers in molecular biosciences2022

Profiling Urinary Sulfate Metabolites With Mass Spectrometry.

Christopher C J Fitzgerald, Rikard Hedman, Dimanthi R Uduwela, Bettina Paszerbovics, Adam J Carroll, Teresa Neeman, Adam Cawley, Lance Brooker, Malcolm D McLeod

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christopher C J FitzgeraldResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Rikard HedmanResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Dimanthi R UduwelaResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Bettina PaszerbovicsResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Adam J CarrollResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Teresa NeemanResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Adam CawleyAustralian Racing Forensic Laboratory, Racing NSW, Sydney, NSW, Australia.
Lance BrookerAustralian Sports Drug Testing Laboratory, National Measurement Institute, Sydney, NSW, Australia.
Malcolm D McLeodResearch School of Chemistry, Australian National University, Acton, ACT, Australia.
Australian National University · AUNational Measurement Institute · AURacing Victoria · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of urinary phase II sulfate metabolites is central to understanding the role and fate of endogenous and exogenous compounds in biological systems. This study describes a new workflow for the untargeted metabolic profiling of sulfated metabolites in a urine matrix. Analysis was performed using ultra-high-performance liquid chromatography-high resolution tandem mass spectrometry (UHPLC-HRMS/MS) with data dependent acquisition (DDA) coupled to an automated script-based data processing pipeline and differential metabolite level analysis. Sulfates were identified through

Indexed as

anti-dopingmass spectrometrymetabolomicssteroidsulfatasesulfate estersulfation

Identifiers

PMID35281273
PMCPMC8906285
OpenAlexW4212788924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.