Evidence map›Paper›PMID 35281141›Full record

ReviewJournal of oral and maxillofacial pathology : JOMFP

Efficacy of herbal alternatives in maintaining oral health in cancer patients: A systematic review.

Nadeem Jeddy, Nirmal Famila Bettie, R Saravanan, L J Sai Lakshmi, T Radhika

Open access · greenAbstract readReview
In one paragraph

Review in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nadeem JeddyDepartment of Oral Pathology and Microbiology, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India.
Nirmal Famila BettieDepartment of Prosthodontics, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India.
R SaravananOrthodontics, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India.
L J Sai LakshmiDepartment of Oral Pathology and Microbiology, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India.
T RadhikaDepartment of Oral Pathology and Microbiology, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India.
Thai Moogambigai Dental College and Hospital · INDr. M.G.R. Educational and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal rinses possess different medicinal properties. Numerous studies have reported the usefulness of various herbal oral rinses. Few studies claimed that herbal rinses are superior to synthetic mouth rinses for certain purposes, but there appears to be a lack of sound scientific evidence to prove the efficacy of herbal rinses in controlling oral plaque in cancer patients. This review analyses the various clinical studies on herbal rinses and aims to find the safety and efficacy of red ginseng mouth rinses over other available mouth rinses in carcinoma patients. A thorough electronic search was conducted in various databases and 10 articles were included in the review based on the inclusion and exclusion criteria. The data extracted were tabulated and analyzed. The risk of bias table was drawn. Meta-analysis was not performed due to the heterogeneity of the included studies. Of the 10 clinical trials included in the review, three studies appeared to have low risk of bias. The mean follow-up period was 14 days, ranging from 7 to 21 days. The sample size in each study was reported to be between 10 and 50, except one study with 240 samples. Seven studies have reported a significant difference between the herbal mouth rinse group and the chlorhexidine group. Of all the herbal rinses, mouth rinses with ginger extracts show more efficacy over other herbal rinses and red ginseng appears to be a more safer herbal rinse. Based on the available evidence, herbal mouth rinses are comparable to synthetic mouth rinses in their anti-bacterial properties. The red ginseng with anti-bacterial, anti-inflammatory and anti-cancerous properties may be an alternative mouth rinse in cancer patients. However, further clinical trials with more samples are required for better evidence.

Indexed as

Cancerginsengherbal alternatives

Identifiers

PMID35281141
PMCPMC8859579
OpenAlexW4205094425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.