Evidence map›Paper›PMID 35281062›Full record

ArticleFrontiers in immunology2022

Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations.

Ee Shan Pang, Ghazal Daraj, Katherine R Balka, Dominic De Nardo, Christophe Macri, Hubertus Hochrein, Kelly-Anne Masterman, Peck S Tan, Angus Shoppee, Zoe Magill and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 24 citations in OpenAlex.

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  17. DNA sensing of dendritic cells in cancer immunotherapy.Frontiers in molecular biosciences · 2024
    Review
  18. Review
  19. Article
  20. A lncRNA identifieseLife · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Ee Shan PangDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Ghazal DarajTranslational Research Institute, Mater Research-University of Queensland, Woolloongabba, QLD, Australia.
Katherine R BalkaDepartment of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Dominic De NardoDepartment of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Christophe MacriDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Hubertus HochreinDepartment of Research, Bavarian Nordic GmbH, Martinsried, Germany.
Kelly-Anne MastermanTranslational Research Institute, Mater Research-University of Queensland, Woolloongabba, QLD, Australia.
Peck S TanDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Angus ShoppeeDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Zoe MagillDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Nazneen JahanDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Mariam BafitDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Yifan ZhanImmunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Benjamin T KileDepartment of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Kate E LawlorCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Kristen J RadfordTranslational Research Institute, Mater Research-University of Queensland, Woolloongabba, QLD, Australia.
Mark D WrightDepartment of Immunology and Pathology, Monash University, Melbourne, VIC, Australia.
Meredith O'KeeffeDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Monash University · AUAustralian Regenerative Medicine Institute · AUTranslational Research Institute · AUBavarian Nordic (Germany) · DEMater Research · AUUniversity of Adelaide · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimulator of Interferon Genes (STING) is a cytosolic sensor of cyclic dinucleotides (CDNs). The activation of dendritic cells (DC)

Indexed as

Interferon Type IAnimalsCell DeathCytosolDendritic CellsHumansMembrane ProteinsMiceSignal TransductionSTING ProteinInterferon Type IMembrane ProteinsSTING1 protein, humanSting1 protein, mouseSTING Proteincell deathdendritic cell (DC)human dendritic cellsinterferon-lambdaplasmacytoid dendritic cells (pDCs)STING activationtype III interferons

Identifiers

PMID35281062
PMCPMC8914948
OpenAlexW4214574231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.