Evidence map›Paper›PMID 35281030›Full record

ArticleFrontiers in immunology2022

Zhishang Meng, Yanzhu Chen, Wenyi Wu, Bin Yan, Lusi Zhang, Huihui Chen, Yongan Meng, Youling Liang, Xiaoxi Yao, Jing Luo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhishang MengDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yanzhu ChenDepartment of Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Wenyi WuDepartment of Ophthalmology, Xiangya Hospital, Central South University, Changsha, China.
Bin YanDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Lusi ZhangDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Huihui ChenDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yongan MengDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Youling LiangDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Xiaoxi YaoShenzhen College of International Education, Shenzhen, China.
Jing LuoDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. UM develops and is sustained by inflammation and immunosuppression from the tumor microenvironment (TME). This study sought to identify a reliable TME-related biomarker that could provide survival prediction and new insight into therapy for UM patients. Based on clinical characteristics and the RNA-seq transcriptome data of 80 samples from The Cancer Genome Atlas (TCGA) database,

Indexed as

Epithelial-Mesenchymal TransitionUveal NeoplasmsHomeodomain ProteinsHumansInflammationMelanomaPrognosisTumor MicroenvironmentUveal MelanomaHomeodomain ProteinsPRRX1 protein, humanbiomarkerepithelial–mesenchymal transitionPRRX1tumor microenvironmentuveal melanoma

Identifiers

PMID35281030
PMCPMC8914230
OpenAlexW4214503874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.