Evidence map›Paper›PMID 35281012›Full record

ArticleFrontiers in immunology2022

STAT6 Blockade Abrogates

Hua Sun, Ashish Damania, Megan L Mair, Eniola Otukoya, Yi-Dong Li, Katherine Polsky, Yuying Zeng, Jeremiah A Alt, Martin J Citardi, David B Corry and 2 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hua SunCenter for Immunology and Autoimmune Diseases, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Ashish DamaniaDepartment of Pediatrics-Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Megan L MairDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
Eniola OtukoyaDepartment of Medicine, Baylor College of Medicine, Houston, TX, United States.
Yi-Dong LiCenter for Immunology and Autoimmune Diseases, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Katherine PolskyDepartment of Medicine, Baylor College of Medicine, Houston, TX, United States.
Yuying ZengDivision of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jeremiah A AltDivision of Otolaryngology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, United States.
Martin J CitardiDepartment of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
David B CorryDepartment of Medicine, Baylor College of Medicine, Houston, TX, United States.
Amber U LuongCenter for Immunology and Autoimmune Diseases, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
John Morgan KnightDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.

Funding

Pathogenesis of Polymicrobial Cerebritis-Related DementiaR01AI135803 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI CORRY, DAVID B, KHERADMAND, FARRAH · 2018 to 2022
$3.8M
Th1 and Th17 Mediators in Experimental EmphysemaR01HL117181 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI CORRY, DAVID B, KHERADMAND, FARRAH · 2013 to 2016
$1.5M
NHLBI NIH HHS R01 HL117181NIAID NIH HHS R01 AI135803
6 · The paper itself

Abstract

Unified airway disease, including concurrent asthma and chronic rhinosinusitis (CRS), is a common, but poorly understood disorder with no curative treatment options. To establish a murine model of chronic unified eosinophilic airway inflammation, mice were challenged with

Indexed as

AsthmaEosinophiliaSinusitisAnimalsAspergillusInflammationLungMiceSTAT6 Transcription FactorStat6 protein, mouseSTAT6 Transcription Factorallergicasthmachronic rhinosinusitiseosinophilmouse modelmycosisSTAT-6unified airway

Identifiers

PMID35281012
PMCPMC8904741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.