ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022
Digitally generated Trail Making Test data: Analysis using hidden Markov modeling.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Article
- Association Between Visit-to-Visit Glucose Variability and Brain Morphology and Cognitive Function in Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2025Article
- Developing an accessible dementia assessment tool: Leveraging a residual network, the trail making test, and demographic data.Journal of Alzheimer's disease : JAD · 2025Article
- Exploring the Nexus Between Alcohol Consumption, Sleep Deprivation, and Memory Among Male Students at a Tertiary Institution in Ghana.Brain and behavior · 2025Article
- Identification of novel protective loci for executive function using the trail making test part B in the Long Life Family Study.bioRxiv : the preprint server for biology · 2025Article
- Effectiveness of digital screening tools in detecting cognitive impairment among community-dwelling elderly in Northern China: A large cohort study.The journal of prevention of Alzheimer's disease · 2025Article
- Association of Cerebral Hypoperfusion and Poor Collaterals with Cognitive Impairment in Patients with Severe Vertebrobasilar Artery Stenosis.Journal of Alzheimer's disease reports · 2024Article
- Predicting Conversion Time from Mild Cognitive Impairment to Dementia with Interval-Censored Models.Journal of Alzheimer's disease : JAD · 2024Article
- Dysexecutive difficulty and subtle everyday functional disabilities: the digital Trail Making Test.Frontiers in neurology · 2024Article
- Digitally generated Trail Making Test data: Analysis using hidden Markov modeling.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Disease progression from mild cognitive impairment to dementia for patients with Alzheimer's disease or Lewy body pathology.Journal of Alzheimer's disease reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The Trail Making Test (TMT) is a neuropsychological test used to assess cognitive dysfunction. The TMT consists of two parts: TMT-A requires connecting numbers 1 to 25 sequentially; TMT-B requires connecting numbers 1 to 12 and letters A to L sequentially, alternating between numbers and letters. We propose using a digitally recorded version of TMT to capture cognitive or physical functions underlying test performance. We analyzed digital versions of TMT-A and -B to derive time metrics and used Bayesian hidden Markov models to extract additional metrics. We correlated these derived metrics with cognitive and physical function scores using regression. On both TMT-A and -B, digital metrics associated with graphomotor processing test scores and gait speed. Digital metrics on TMT-B were additionally associated with episodic memory test scores and grip strength. These metrics provide additional information of cognitive state and can differentiate cognitive and physical factors affecting test performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.