Evidence map›Paper›PMID 35280955›Full record

ArticleBeilstein journal of organic chemistry2022

Trichloroacetic acid fueled practical amine purifications.

Aleena Thomas, Baptiste Gasch, Enzo Olivieri, Adrien Quintard

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aleena ThomasAix-Marseille Univ, CNRS, Centrale Marseille, iSm2, Marseille, France.
Baptiste GaschAix-Marseille Univ, CNRS, Centrale Marseille, iSm2, Marseille, France.
Enzo OlivieriAix-Marseille Univ, CNRS, Centrale Marseille, iSm2, Marseille, France.ORCID https://orcid.org/0000-0002-9968-2245
Adrien QuintardAix-Marseille Univ, CNRS, Centrale Marseille, iSm2, Marseille, France.ORCID https://orcid.org/0000-0003-0193-6524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amine purification have for long been dominated by tedious stepwise processes involving the generation of large amounts of undesired waste. Inspired by recent work on out of equilibrium molecular machinery, using trichloroacetic acid (TCA), we disclose a purification technique considerably decreasing the number of operations and the waste generation required for such purifications. At first, TCA triggers the precipitation of the amines through their protonated salt formation, enabling the separation with the impurities. From these amine salts, simple decarboxylation of TCA liberates volatile CO

Indexed as

aminesdecarboxylationeco-compatibleout of equilibriumpurification

Identifiers

PMID35280955
PMCPMC8895030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.