Evidence map›Paper›PMID 35280903›Full record

ArticleFrontiers in medicine2022

Mortality Among Hospitalized Patients With Pleural Effusions. A Multicenter, Observational, Prospective Study.

Eleftherios Markatis, Garifallia Perlepe, Andreas Afthinos, Konstantinos Pagkratis, Charalampos Varsamas, Eleftheria Chaini, Ilias C Papanikolaou, Konstantinos I Gourgoulianis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eleftherios MarkatisPulmonary Department, Corfu General Hospital, Corfu, Greece.
Garifallia PerlepeDepartment of Respiratory Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Andreas AfthinosPulmonary Department, Corfu General Hospital, Corfu, Greece.
Konstantinos PagkratisPulmonary Department, Corfu General Hospital, Corfu, Greece.
Charalampos VarsamasDepartment of Respiratory Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Eleftheria ChainiPulmonary Department, Corfu General Hospital, Corfu, Greece.
Ilias C PapanikolaouPulmonary Department, Corfu General Hospital, Corfu, Greece.
Konstantinos I GourgoulianisDepartment of Respiratory Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Corfu General Clinic · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data regarding the prognostic significance of pleural effusion (PE) are scarce. Objective: Explore the impact of PE on mortality among hospitalized patients. Methods: Multicenter prospective observational study. Patients that underwent computed tomography (thorax and/or abdomen) and in which PE was detected, were admitted to the study. PE was classified by size on CT, anatomical distribution, diagnosis, and Light's criteria. Charlson comorbidity index (CCI), APACHE II, and SOFA score were calculated. Mortality at 1 month and 1 year were recorded. Results: Five hundred and eight subjects, mean age 78 years. Overall mortality was 22.6% at 1 month and 49.4% at 1 year. Bilateral effusions were associated with higher mortality than unilateral effusions at 1 month (32 vs. 13.3%, Conclusions: Pleural effusion is a marker of advanced disease. Mortality is higher within the first month in patients with PEs related to organ failure, while patients with MPE have the worst long-term outcome. Independent predictors of mortality, apart from CCI, APACHE II, and SOFA scores, are age and bilateral distribution in the short-term, and malignancy in the long-term.

Indexed as

hospitalized patients (inpatients)mortalitypleural effusionprognostic factorssurvival

Identifiers

PMID35280903
PMCPMC8907663
OpenAlexW4213446302

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.