Evidence map›Paper›PMID 35280791›Full record

ArticleFrontiers in oncology2022

Differentiation Between Benign and Metastatic Breast Lymph Nodes Using Apparent Diffusion Coefficients.

Reza Fardanesh, Sunitha B Thakur, Varadan Sevilimedu, Joao V Horvat, Roberto Lo Gullo, Jeffrey S Reiner, Sarah Eskreis-Winkler, Nikita Thakur, Katja Pinker

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Axillary Lymphadenopathy after COVID-19 Vaccination: Follow-up for Enlarged Lymph Nodes on MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  7. Article
  8. Update on DWI for Breast Cancer Diagnosis and Treatment Monitoring.AJR. American journal of roentgenology · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Reza FardaneshDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Sunitha B ThakurDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Varadan SevilimeduDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Joao V HorvatDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Roberto Lo GulloDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Jeffrey S ReinerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Sarah Eskreis-WinklerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Nikita ThakurDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Katja PinkerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The aim of this study was to determine the range of apparent diffusion coefficient (ADC) values for benign axillary lymph nodes in contrast to malignant axillary lymph nodes, and to define the optimal ADC thresholds for three different ADC parameters (minimum, maximum, and mean ADC) in differentiating between benign and malignant lymph nodes. This retrospective study included consecutive patients who underwent breast MRI from January 2017-December 2020. Two-year follow-up breast imaging or histopathology served as the reference standard for axillary lymph node status. Area under the receiver operating characteristic curve (AUC) values for minimum, maximum, and mean ADC (min ADC, max ADC, and mean ADC) for benign

Indexed as

apparent diffusion coefficientbreast cancerdiffusion-weighted imaginglymph nodesMRIprognostic factors

Identifiers

PMID35280791
PMCPMC8905522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.