Evidence map›Paper›PMID 35280722›Full record

ArticleFrontiers in oncology2022

Impact of Race and Geographic Area of Residence on Outcomes After Allogeneic Stem Cell Transplant.

Audrey M Sigmund, Qiuhong Zhao, Justin Jiang, Patrick Elder, Don M Benson, Ashley Rosko, Naresh Bumma, Abdullah Khan, Srinivas Devarakonda, Sumithira Vasu and 11 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Acute graft-versus-host disease.Nature reviews. Disease primers · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Audrey M SigmundDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Qiuhong ZhaoDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Justin JiangCollege of Medicine, The Ohio State University, Columbus, OH, United States.
Patrick ElderDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Don M BensonDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Ashley RoskoDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Naresh BummaDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Abdullah KhanDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Srinivas DevarakondaDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Sumithira VasuDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Samantha JaglowskiDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Alice MimsDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Hannah ChoeDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Karilyn LarkinDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Jonathan BrammerDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Sarah WallDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Nicole GrieselhuberDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Ayman SaadDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Sam PenzaDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Yvonne A EfeberaDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Nidhi SharmaDivision of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

Background: Allogeneic hematopoietic stem cell transplant (allo-HCT) is a potential curative therapy for a variety of hematologic disorders. However, it requires highly specialized care that is only available at select centers across the country. Thus, minority populations are at risk for healthcare disparities in access to and outcomes of allo-HCT. Our study aimed to assess the impact of race and location of residence on outcomes of allo-HCT. Methods: We performed a retrospective analysis of all patients who underwent allo-HCT at the Ohio State University from 1984 to 2018. Patients were divided by race (Caucasian, African American, and other) and grouped by zip code into rural, suburban, and urban groups. Primary endpoints included progression-free survival (PFS) and overall survival (OS). Results: Of the 1,943 patients included in the study, 94.3% self-identified as Caucasian, 4.6% African American, and 1.1% other. In total, 63.4% lived in rural areas, 22.9% suburban, and 13.8% urban. There was no significant difference in OS or PFS by race ( Conclusion: Our study suggests that when appropriate access to HCT is given, there is no difference in outcomes based on race, ethnicity or place of primary residence. Further research is needed to further evaluate barriers for these patients to undergo transplant and help mitigate these barriers.

Indexed as

allogeneic transplantgeographic location of residenceGvHDhealth disparitiesrace

Identifiers

PMID35280722
PMCPMC8913574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.