Evidence map›Paper›PMID 35280688›Full record

ReviewInternational journal of biological sciences2022

Advances in Multi-Omics Study of Prognostic Biomarkers of Diffuse Large B-Cell Lymphoma.

Xiao-Jie Liang, Xin-Yu Song, Jia-Lin Wu, Dan Liu, Bing-Yu Lin, Hong-Sheng Zhou, Liang Wang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 38 citations in OpenAlex.

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  9. Clinical value of ENO2 in serum extracellular vesicles for the diagnosis and prognosis of diffuse large B-cell lymphoma patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Xiao-Jie LiangDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xin-Yu SongThe First Clinical Medical College, Guangdong Medical University, Zhanjiang 524000, China.
Jia-Lin WuDepartment of Interventional Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Dan LiuThe First Clinical Medical College, Guangdong Medical University, Zhanjiang 524000, China.
Bing-Yu LinThe First Clinical Medical College, Guangdong Medical University, Zhanjiang 524000, China.
Hong-Sheng ZhouDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Liang WangDepartment of Hematology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Guangdong Medical College · CNNanfang Hospital · CNBeijing Tongren Hospital · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the most common subtype of non-Hodgkin's lymphoma, diffuse large B-cell lymphoma (DLBCL) is characterized by a huge degree of clinical and prognostic heterogeneity. Currently, there is an urgent need for highly specific and sensitive biomarkers to predict the therapeutic response of DLBCL and assess which patients can benefit from systemic chemotherapy to help develop more precise therapeutic regimens for DLBCL. Systems biology (holistic study of diseases) is more comprehensive in quantifying and identifying biomarkers, helps addressing major biological problems, and possesses high accuracy and sensitivity. In this article, we provide an overview of research advances in DLBCL prognostic biomarkers made using the multi-omics approach of genomics, transcriptomics, epigenetics, proteomics, metabonomics, radiomics, and the currently developing single-cell technologies.

Indexed as

Lymphoma, Large B-Cell, DiffuseAntineoplastic Combined Chemotherapy ProtocolsBiomarkersBiomarkers, TumorHumansPrognosisBiomarkersBiomarkers, TumorBiomarkersDiffuse large B cell lymphomaPrecision medicinePrognosisSystems biology

Identifiers

PMID35280688
PMCPMC8898353
OpenAlexW4206773816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.