Evidence map›Paper›PMID 35280442›Full record

SynthesisDisease markers2022

Neoadjuvant Chemotherapy for Different Stages of Muscle-Invasive Bladder Cancer: A Systematic Review and Meta-analysis.

Shuai Liu, Yu Yao, Fengju Guan, Lijiang Sun, Guiming Zhang

Open access · hybridAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shuai LiuDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yu YaoDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Fengju GuanDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lijiang SunDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Guiming ZhangDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0002-5856-5325
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this meta-analysis is to determine the survival benefits and pathological outcomes of neoadjuvant chemotherapy (NAC) combined with radical cystectomy (RC) administered to patients with cT2 or cT3-4N0M0 muscle-invasive bladder cancer (MIBC). PubMed, Embase, and the Cochrane Library were searched for comparing the use of NAC in combination with RC and RC alone in patients with different MIBC stages. A fixed effects model was used to calculate hazard ratio (HR) and odds ratio (OR) with 95% confidence intervals (CIs), and the

Indexed as

CystectomyNeoadjuvant TherapyHumansNeoplasm StagingTreatment OutcomeUrinary Bladder Neoplasms

Identifiers

PMID35280442
PMCPMC8906988
OpenAlexW4214932218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.