Evidence map›Paper›PMID 35280432›Full record

ArticleNature and science of sleep2022

Clinical Predictors of Mixed Apneas in Patients with Obstructive Sleep Apnea (OSA).

Pengfei Liu, Quanhui Chen, Fang Yuan, Qingru Zhang, Xiaoying Zhang, Chan Xue, Yuqing Wei, Yakun Wang, Hanqiao Wang

Open access · goldAbstract read
In one paragraph

Article in Nature and science of sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Analytical amplitude/phase markers for neurological sleep apnea events.Neurobiology of sleep and circadian rhythms · 2026
    Article
  2. The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Article
  5. Central and mixed apneas in children with obstructive sleep apnea: effect of adenotonsillectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Observational
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pengfei Liu *Department of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.ORCID 0000-0001-5302-1188
Quanhui Chen *Department of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Fang YuanDepartment of Physiology, Hebei Key Laboratory of Neurophysiology, Shijiazhuang, Hebei, People's Republic of China.
Qingru ZhangDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Xiaoying ZhangDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Chan XueDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Yuqing WeiDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Yakun WangDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Hanqiao WangDepartment of Sleep Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Mixed events in obstructive sleep apnea (OSA) patients (mixed-OSA) indicate respiratory regulation instability and are essential for OSA pathogenesis and prognosis. It also shows a decreased compliance with continuous positive airway pressure (CPAP). Using predictors to identify mixed-OSA has significant clinical guidance for OSA precise diagnosis and treatment. This study aimed to establish a simple and accessible method for rapid screening of mixed-OSA, thus promoting OSA precise diagnosis. Patients and Methods: A total of 907 patients with suspected OSA were screened, of which 513 OSA patients, including 344 with pure-OSA and 169 with mixed-OSA, were finally included in the study. The clinical characteristics and polysomnography (PSG) parameters of the two OSA groups were compared. Multivariate logistic regression analysis was used to investigate the factors affecting the morbidity of mixed-OSA. The receiver operating characteristic (ROC) curve was used to explore if some convenient PSG parameters can be used to predict mixed-OSA. Results: About 33% of OSA patients were identified as mixed-OSA. Multivariate logistic regression analysis showed that apnea hypopnea index (AHI) and lowest oxygen saturation (LSO Conclusion: Our research found that AHI > 47 or LSO

Indexed as

apnea hypopnea indexlowest saturationmixed eventsprecise individual diagnosis

Identifiers

PMID35280432
PMCPMC8906897
OpenAlexW4214840588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.