ArticleFrontiers in neurology2022
Application of Three-Dimensional Pseudocontinuous Arterial Spin Labeling Perfusion Imaging in the Brains of Children With Autism.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Evaluation of Brain Microstructural Alterations in Preschool Autism Spectrum Disorder: A Voxel-Wise Multimodal MRI Study.Journal of magnetic resonance imaging : JMRI · 2026Article
- Cerebral blood flow changes and their genetic mechanisms in autism spectrum disorder: a combined neuroimaging and transcriptome study.European archives of psychiatry and clinical neuroscience · 2025Article
- Application of eye and hand interventions in brain magnetic resonance imaging of young children.Heliyon · 2024Article
- [Neurodevelopment and cerebral blood flow in children aged 2-6 years with autism spectrum disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Modelling the overlap and divergence of autistic and schizotypal traits on hippocampal subfield volumes and regional cerebral blood flow.Molecular psychiatry · 2024Article
- Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder.Frontiers in psychiatry · 2024Review
- Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism.Metabolic brain disease · 2023Article
- Application of Multimodal MRI in the Early Diagnosis of Autism Spectrum Disorders: A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Three-dimensional pseudocontinuous arterial spin labeling perfusion imaging shows cerebral blood flow perfusion decline in attention-deficit/hyperactivity disorder children.Frontiers in psychiatry · 2023Article
- Diagnosis of children with attention-deficit/hyperactivity disorder (ADHD) comorbid autistic traits (ATs) by applying quantitative magnetic resonance imaging techniques.Frontiers in psychiatry · 2022Article
- Application of pseudocontinuous arterial spin labeling perfusion imaging in children with autism spectrum disorders.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To explore the application of three-dimensional pseudocontinuous arterial spin labeling (3D-PCASL) perfusion imaging in the brains of children with autism and to understand the characteristics of cerebral blood perfusion in children with autism. Methods: A total of 320 children with autism (160 men and 160 women) aged between 2 and 18 years and 320 age- and sex-matched healthy children participated in the study. All children were scanned by 3.0 T magnetic resonance axial T1 fluid-attenuated inversion recovery (FLAIR), T2 FLAIR, 3D-T1, and 3D-PCASL sequences. After postprocessing, cerebral blood flow (CBF) values in each brain region of children with autism and healthy children at the same age were compared and analyzed. Furthermore, CBF characteristics in each brain region of autistic children at various ages were determined. Results: The CBF values of the frontal lobe, hippocampus, temporal lobe, and caudate nucleus of children with autism are lower than those of healthy children ( Conclusion: The 3D-PCASL shows lower brain CBF values in children with autism. Clinical Trial Registration: www.ClinicalTrials.gov, identifier: ChiCTR2000034356.
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