Evidence map›Paper›PMID 35280086›Full record

ArticleClinical case reports2022

Very rare near-haploid acute lymphoblastic leukemia resistant to immunotherapy and CAR-T therapy in 19-year-old male patient.

Tomas Arpas, Hana Jelinkova, Stepan Hrabovsky, Martina Orsulova, Zuzana Vrzalova, Veronika Navrkalova, Eva Brhelova, Lenka Bryjova, Alena Bulikova, Eva Ondrouskova and 7 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Tomas ArpasDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0002-5198-0307
Hana JelinkovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Stepan HrabovskyDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Martina OrsulovaDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Zuzana VrzalovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Veronika NavrkalovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0003-3020-1578
Eva BrhelovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Lenka BryjovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0002-8108-9750
Alena BulikovaDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Eva OndrouskovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0003-0830-0692
Marketa SejnohovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Frantisek FolberDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Petra SedováDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Jiri MayerDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Sarka PospisilovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.
Marie JarosovaCenter of Molecular Biology and Genetics Department of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0002-2194-3433
Michael DoubekDepartment of Internal Medicine, Hematology and Oncology University Hospital and Faculty of Medicine Brno Czechia.ORCID https://orcid.org/0000-0002-1269-6282
University Hospital Brno · CZCentral European Institute of Technology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-haploid acute lymphoblastic leukemia is rare subgroup of the disease, which is very important due to very poor prognosis and resistance to treatment including novel monoclonal antibodies and CAR-T therapy.

Indexed as

acute lymphoblastic leukemiablinatumomabCAR‐T therapyinotuzumab ozogamicinnear‐haploid

Identifiers

PMID35280086
PMCPMC8894580
OpenAlexW4214912388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.