ArticleJournal of cancer survivorship : research and practice2023
Long-term trajectory of postoperative health-related quality of life in young breast cancer patients: a 15-year follow-up study.
Article in Journal of cancer survivorship : research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Which specific modes of exercise training are most effective for breast related cancer fatigue? Network meta-analysis.Frontiers in oncology · 2025Pooled it
- Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care.Systematic reviews · 2024Pooled it
- Various interventions for cancer-related fatigue in patients with breast cancer: a systematic review and network meta-analysis.Frontiers in oncology · 2024Pooled it
- Feasibility of patient-reported outcomes collection in clinical routine at a radiotherapy department.Acta oncologica (Stockholm, Sweden) · 2026Article
- Article
- Factors affecting health-related quality of life following axillary lymph node dissection among breast cancer survivors in Egypt.Scientific reports · 2025Article
- The need for comprehensive sleep disturbances assessment and management in breast cancer care.Scientific reports · 2025Observational
- Refining the interpretation of post-radiotherapy urinary and bowel outcomes in prostate cancer: A clinical perspective.Clinical and translational radiation oncology · 2025Article
- Advancing breast cancer rehabilitation: a novel tool for assessing physical morbidity risk.The oncologist · 2025Article
- Health-related quality of life among women diagnosed with in situ or invasive breast cancer and age-matched controls: a population-based study.Journal of patient-reported outcomes · 2024Article
- Is it really over when it is over? physical, mental and emotional health status of long-term breast cancer survivors compared to healthy matched controls.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Making sense of the cancer journey: Pediatric cancer survivors' and their parents' autobiographical memories.Journal of cancer survivorship : research and practice · 2024Article
- Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study.Cancers · 2023Article
- Beneficial Exercises for Cancer-Related Fatigue among Women with Breast Cancer: A Systematic Review and Network Meta-Analysis.Cancers · 2022Review
- Effect of a telehealth-based exercise intervention on the physical activity of patients with breast cancer: A systematic review and meta-analysis.Asia-Pacific journal of oncology nursing · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBreast cancer (BC) patients often experience various long-term sequelae due to aggressive treatment. We analyzed and illustrated long-term trajectory during different phases of treatment and survivorship.
methodsData were obtained from a cohort of 298 BC patients diagnosed between 2004 and 2006 and were followed up until 2020. We measured HRQoL using EORTC QLQ-C30, QLQ-BR23, and EuroQoL-5D questionnaires and conducted eight assessments right after initial diagnosis, during treatment, post-treatment, and during survivorship phases. Linear mixed model was used to assess changes in HRQoL. Overall HRQoL measured by EQ-5D index of long-term BC survivors were further compared with that of the age-matched general population.
resultsOf 298 participants, 246 women survived and 124 participated in the long-term follow-up survey (LTFU). Overall, HRQoL functions deteriorated during treatment but gradually improved between 1- and 3-year post-diagnosis and stabilized over LTFU measure. Significant recovery was observed in physical, role, emotional, social functions, and future perspectives (p < 0.05). Treatment-related acute symptoms were reported in the first year but diminished afterward, and treatment-related financial difficulties lessened. At LTFU, BC survivors reported a high level of insomnia, fatigue, and pain and appeared to have poorer overall HRQoL than the general population (mean difference, EQ-5D index: 0.073, p < 0.001).
conclusionsThrough 15-year survivorship, BC survivors showed improvement in many aspects of HRQoL. However, some inferior aspects remain relevant for long-term survivors. Ongoing supportive programs concentrating on pain management, persistent cancer-related fatigue, and sleeping problems might aid enhance their HRQoL.
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