Evidence map›Paper›PMID 35279732›Full record

ArticleWorld journal of urology2022

Minimally invasive retroperitoneal lymph node dissection for men with testis cancer: a retrospective cohort study of safety and feasibility.

Christian D Fankhauser, Luca Afferi, Sean P Stroup, Nicholas R Rocco, Kathleen Olson, Aditya Bagrodia, Fady Baky, Walter Cazzaniga, Erik Mayer, David Nicol and 19 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Laparoscopic Bilateral Nerve-Sparing Retroperitoneal Lymph Node Dissection for Testicular Cancer After Chemotherapy.International journal of urology : official journal of the Japanese Urological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 17 institutions in 8 countries.

Christian D FankhauserDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland. cdfankhauser@gmail.com.ORCID http://orcid.org/0000-0002-4073-5488
Luca AfferiDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Sean P StroupDepartment of Urology, Naval Medical Center San Diego, San Diego, CA, USA.
Nicholas R RoccoDepartment of Urology, Naval Medical Center San Diego, San Diego, CA, USA.
Kathleen OlsonDepartment of Urology, Mayo Clinic Hospital, Phoenix, AZ, USA.
Aditya BagrodiaDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Fady BakyDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Walter CazzanigaDepartment of Urology, The Royal Marsden NHS Foundation Trust, London, Sutton, UK.
Erik MayerDepartment of Urology, The Royal Marsden NHS Foundation Trust, London, Sutton, UK.
David NicolDepartment of Urology, The Royal Marsden NHS Foundation Trust, London, Sutton, UK.
Ekrem IslamogluDepartment of Urology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey.
Stephane de VergieDepartment of Urology and Transplantation Surgery, University Hospital Center, Nantes, France.
Ragheed SaoudSection of Urology, Department of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Scott E EggenerSection of Urology, Department of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Sebastiano NazzaniDepartment of Urology, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milano, Italy.
Nicola NicolaiDepartment of Urology, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milano, Italy.
Lee HugarDepartment of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Wade J SextonDepartment of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Deliu-Victor MateiDepartment of Urology, European Institute of Oncology, Milan, Italy.
Ottavio De CobelliDepartment of Urology, European Institute of Oncology, Milan, Italy.
Joseph CheaibDepartment of Urology, The Johns Hopkins Medical Institutions and The James Brady Buchannan Urological Institute, Baltimore, MD, USA.
Phillip M PierorazioDepartment of Urology, The Johns Hopkins Medical Institutions and The James Brady Buchannan Urological Institute, Baltimore, MD, USA.
James PorterDepartment of Urology, Department of Urology, University of Washington School of Medicine, Seattle, WA, USA.
Thomas HermannsDepartment of Urology, University of Zurich, Zurich, Switzerland.
Robert J HamiltonDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Andreas HiesterDepartment of Urology, Medical Faculty, University of Duesseldorf, Heinrich-Heine-University, Duesseldorf, Germany.
Peter AlbersDepartment of Urology, Medical Faculty, University of Duesseldorf, Heinrich-Heine-University, Duesseldorf, Germany.
Noel ClarkeDepartment of Urology, The Christie NHS Foundation Trust, Manchester, UK.
Agostino MatteiDepartment of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
Luzerner Kantonsspital · CHRoyal Marsden NHS Foundation Trust · GBEuropean Institute of Oncology · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITHeinrich Heine University Düsseldorf · DEJohns Hopkins University · USMoffitt Cancer Center · USNaval Medical Center San Diego · USThe University of Texas Southwestern Medical Center · USUniversity of Chicago Medical Center · USAntalya Eğitim ve Araştırma Hastanesi · TRInstitut de Transplantation Urologie en Nephrologie · FRMayo Clinic Hospital · USThe Christie NHS Foundation Trust · GBUniversity of Toronto · CAUniversity of Washington · USUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the perioperative safety, functional and immediate post-operative oncological outcomes of minimally invasive RPLND (miRPLND) for testis cancer.

methodsWe performed a retrospective multi-centre cohort study on testis cancer patients treated with miRPLND from 16 institutions in eight countries. We measured clinician-reported outcomes stratified by indication. We performed logistic regression to identify predictors for maintained postoperative ejaculatory function.

resultsData for 457 men undergoing miRPLND were studied. miRPLND comprised laparoscopic (n = 56) or robotic (n = 401) miRPLND. Indications included pre-chemotherapy in 305 and post-chemotherapy in 152 men. The median retroperitoneal mass size was 32 mm and operative time 270 min. Intraoperative complications occurred in 20 (4%) and postoperative complications in 26 (6%). In multivariable regression, nerve sparing, and template resection improved ejaculatory function significantly (template vs bilateral resection [odds ratio (OR) 19.4, 95% confidence interval (CI) 6.5-75.6], nerve sparing vs non-nerve sparing [OR 5.9, 95% CI 2.3-16.1]). In 91 men treated with primary RPLND, nerve sparing and template resection, normal postoperative ejaculation was reported in 96%. During a median follow-up of 33 months, relapse was detected in 39 (9%) of which one with port site (< 1%), one with peritoneal recurrence and 10 (2%) with retroperitoneum recurrences.

conclusionThe low proportion of complications or peritoneal recurrences and high proportion of men with normal postoperative ejaculatory function supports further miRPLND studies.

Indexed as

Neoplasms, Germ Cell and EmbryonalTesticular NeoplasmsCohort StudiesFeasibility StudiesHumansLymph Node ExcisionMaleNeoplasm Recurrence, LocalRetroperitoneal SpaceRetrospective StudiesTreatment OutcomeGerm cell tumoursRetroperitoneal lymph node dissectionRobotic surgeryRPLNDTestis cancer

Identifiers

PMID35279732
OpenAlexW4220721924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.