Evidence map›Paper›PMID 35279731›Full record

ArticleWorld journal of urology2022

Prospective quality of life in men choosing open vs. robotic radical prostatectomy: long-term results from a racially diverse multi-institutional database.

Eyal Kord, Nate Jung, Brock Boehm, Galen Conti, Huai-Ching Kuo, Jason Frankel, John Flores, Katherine Levie, On Ho, Sally Elsamanoudi and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Eyal KordDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA. Eyalkord@gmail.com.ORCID http://orcid.org/0000-0001-7361-1636
Nate JungDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.
Brock BoehmWalter Reed National Military Medical Center, Bethesda, MD, USA.
Galen ContiCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Huai-Ching KuoCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Jason FrankelDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.
John FloresDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.
Katherine LevieDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.
On HoDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.
Sally ElsamanoudiCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Jiji JiangCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Sean P StroupCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
John MusserCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Alexander ErnestCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Ryan SpeirCenter for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Gregory ChesnutWalter Reed National Military Medical Center, Bethesda, MD, USA.
Timothy J TauschWalter Reed National Military Medical Center, Bethesda, MD, USA.
Christopher PorterDepartment of Urology, Virginia Mason Franciscan Health, Virginia Mason Hospital and Seattle Medical Center, 1100 Ninth Ave., Seattle, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare 5-year health-related quality of life (HRQoL) outcomes between prostate cancer (CaP) patients who underwent robotic-assisted laparoscopic radical prostatectomy (RALP) versus open radical retropubic prostatectomy (RRP) and assess for racial disparities between Caucasian American (CA) and African American (AA) men undergoing surgery.

methodsA prospective cohort study of HRQoL data was conducted on patients diagnosed with CaP from 2007 to 2017 and enrolled in the Center for Prostate Disease Research (CPDR) Multicenter National Database. Using the EPIC and SF-36 instruments, changes in urinary, sexual, bowel, and hormonal domains, as well as physical and mental component summary scores were compared across surgery type (RALP versus RRP) at pre-treatment ("baseline"), and annually for 5 years. We further compared HRQoL outcomes in CA and AA men undergoing surgery. Longitudinal HRQoL patterns were modeled using generalized estimating equations (GEE), adjusting for baseline HRQoL and other characteristics.

results448 CaP patients (22% AA) met study inclusion criteria, 66% underwent RALP and 34% underwent RRP. At baseline, HRQoL domains were comparable across treatment group (RALP vs. RRP). In the adjusted low-risk cohort, there were only three time points that met a statistically significant HRQoL difference in EPIC scores between RALP and RRP. Urinary function score during year 4 of follow-up showed a 7.5 (95% CI 3.1-11.9, P = 0.01) points difference in favor of RRP. Bowel bother scores favored RRP in year 1 with a difference of 3.1 (95% CI 0.7-5.4, P = 0.04) points, and in year 5 with a difference of 3.8 (95% CI 1.1-6.4, P = 0.03) points. In the intermediate/high-risk cohort, there were no statistically significant differences in any of the domain scores between RALP and RRP during follow-up.

conclusionsThe robotic and open approach to radical prostatectomy led to comparable HRQoL outcomes at a follow-up length of 60 months. No HRQoL racial disparities were found between AA and CA men during long-term follow-up.

Indexed as

LaparoscopyProstatic NeoplasmsRobotic Surgical ProceduresHumansMaleProspective StudiesProstateProstatectomyQuality of LifeTreatment OutcomeProstate cancerQuality of lifeRadical prostatectomy

Identifiers

PMID35279731

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.