Evidence map›Paper›PMID 35279707›Full record

ArticleSoft matter2022

Passive high-frequency microrheology of blood.

Jose Rafael Guzman-Sepulveda, Mahed Batarseh, Ruitao Wu, William M DeCampli, Aristide Dogariu

Open access · hybridAbstract read
In one paragraph

Article in Soft matter, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jose Rafael Guzman-SepulvedaCREOL, The College of Optics and Photonics, University of Central Florida, 4304 Scorpius, Orlando, Florida, 32816, USA. adogariu@creol.ucf.edu.ORCID http://orcid.org/0000-0001-7120-8253
Mahed BatarsehCREOL, The College of Optics and Photonics, University of Central Florida, 4304 Scorpius, Orlando, Florida, 32816, USA. adogariu@creol.ucf.edu.
Ruitao WuCREOL, The College of Optics and Photonics, University of Central Florida, 4304 Scorpius, Orlando, Florida, 32816, USA. adogariu@creol.ucf.edu.
William M DeCampliPediatric Cardiothoracic Surgery, The Heart Center, Arnold Palmer Hospital for Children, Orlando, Florida, USA.
Aristide DogariuCREOL, The College of Optics and Photonics, University of Central Florida, 4304 Scorpius, Orlando, Florida, 32816, USA. adogariu@creol.ucf.edu.ORCID http://orcid.org/0000-0002-2709-9632
University of Central Florida · US

Funding

Real-time monitoring of blood viscoelasticity index during cardiopulmonary bypassR21HL124486 · NHLBI · UNIVERSITY OF CENTRAL FLORIDA · PI DECAMPLI, WILLIAM MICHAEL, DOGARIU, ARISTIDE C · 2015 to 2016
$395k
NHLBI NIH HHS R21 HL124486
6 · The paper itself

Abstract

Indicative of various pathologies, blood properties are under intense scrutiny. The hemorheological characteristics are traditionally gauged by bulk, low-frequency indicators that average out critical information about the complex, multi-scale, and multi-component structure. In particular, one cannot discriminate between the erythrocytes contribution to global rheology and the impact of plasma. Nevertheless, in their fast stochastic movement, before they encounter each other, the erythrocytes probe the subtle viscoelasticity of their protein-rich environment. Thus, if these short time scales can be resolved experimentally, the plasma properties could be determined without having to separate the blood components; the blood is practically testing itself. This microrheological description of blood plasma provides a direct link between the composition of whole blood and its coagulability status. We present a parametric model for the viscoelasticity of plasma, which is probed by the erythrocytes over frequency ranges of kilohertz in a picoliter-sized volume. The model is validated both

Indexed as

ErythrocytesRheologyViscosity

Identifiers

PMID35279707
PMCPMC8941587
OpenAlexW4220760522

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.