ArticleScientific reports2022
Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio).
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Proximity in mice induced by an auditory-conditioned stimulus.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Nonapeptide cell size differs between male morphs of the West African cichlid, Pelvicachromis pulcher.Journal of fish biology · 2026Article
- Distinct distributed neural dynamics predict pallium-dependent social approach.Nature communications · 2026Article
- Review
- Oxidative Stress, Genetic Factors and Behavioral Responses to Chemical Exposure: Insights into Cancer Development in Zebrafish (Danio Rerio).Biochemical genetics · 2026Review
- Preliminary Data Regarding the Potential of Oxytocin to Modulate Aggressive Behaviour in a VPA-Based Animal Model of Autism Spectrum Disorder.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Affiliation in mice induced by an auditory-conditioned stimulus.bioRxiv : the preprint server for biology · 2026Article
- Convergent thyroid-ATPase interactions regulate collective behavior in Danionella.Cell reports · 2026Article
- Zebrafish as a translational model for peptide-mediated synaptic dysfunction related to obesity.Frontiers in synaptic neuroscience · 2026Review
- Oxytocinergic Signaling in Zebrafish: Translational Perspectives for Autism Spectrum Disorder.Journal of neurochemistry · 2026Review
- Social maintenance masks induced aggression in zebrafish.Scientific reports · 2025Article
- LinkedbioRxiv : the preprint server for biology · 2025Article
- Experimental PTSD Models in Zebrafish: A Systematic Review of Behavioral, Neurochemical, and Molecular Outcomes.Biology · 2025Review
- Single-Cell Peptide Profiling to Distinguish Stickleback Ecotypes with Divergent Breeding Behavior.Journal of proteome research · 2025Article
- The Impact of Oxytocin on Stimulus Discrimination of Zebrafish Albino and Non-Albino Models.International journal of molecular sciences · 2025Article
- Review
- Development of neural circuits for social motion perception in schooling fish.Current biology : CB · 2024Article
- Speckle statistics as a tool to distinguish collective behaviors of Zebrafish shoals.Scientific reports · 2024Article
- Effect of Enriched Environment on Cerebellum and Social Behavior of Valproic Zebrafish.NeuroSci · 2024Article
- Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zebrafish are highly social teleost fish and an excellent model to study social behavior. The neuropeptide Oxytocin is associated different social behaviors as well as disorders resulting in social impairment like autism spectrum disorder. However, how Oxytocin receptor signaling affects the development and expression kinetics of social behavior is not known. In this study we investigated the role of the two oxytocin receptors, Oxtr and Oxtrl, in the development and maintenance of social preference and shoaling behavior in 2- to 8-week-old zebrafish. Using CRISPR/Cas9 mediated oxtr and oxtrl knock-out fish, we found that the development of social preference is accelerated if one of the Oxytocin receptors is knocked-out and that the knock-out fish reach significantly higher levels of social preference. Moreover, oxtr
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