Evidence map›Paper›PMID 35279265›Full record

SynthesisThe Lancet. Respiratory medicine2022

Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis.

Davies Adeloye, Peige Song, Yajie Zhu, Harry Campbell, Aziz Sheikh, Igor Rudan, NIHR RESPIRE Global Respiratory Health Unit

6 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Lancet. Respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 814 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
814citing papers in PubMed, 11 pooled it
161.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05947227 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of BBT Versus Diaphragmatic Breathing on Exercise Capacity and Quality of Life in Patients With COPD

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled48ConditionsBreathing TechniqueArmsButeyko breathing technique, Diaphragmatic breathing technique.
NCT06189196 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Blow Bottle Verses ACBTs Technique in Patients of Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled48ConditionsCOPDArmsBLOW BOTTLE, ACBT
NCT06298487 naterminatednot on this mapstarted 2024, after this paper: background citation

Evaluation of the Multidimensional Impact of Therapeutic Education Workshops for COPD Patients, Cared for by the Maison de Prévention de la Santé et d'Accompagnement Thérapeutique, in the North-West Val d'Oise Area

TypeinterventionalSponsorHôpital NOVORan2024 to 2025Enrolled88ConditionsCOPDArmsPatient questionnaires
NCT06308302 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparative Effects of Inspiratory Muscle Training vs Expiratory Muscle Training Along With Aerobic Interval Training on Functional Performance and Fatigue Level in COPD Patients

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled53ConditionsCOPDArmsGroup A (Inspiratory Muscles Training + Aerobic Interval Training), Group B (Expiratory Muscles Training +Aerobic Interval Training)
NCT07402850 nacompletednot on this mapstarted 2025, after this paper: background citation

Oscillating Positive Expiratory Pressure Therapy Versus Autogenic Drainage in Patients With Chronic Obstructive Pulmonary Disease: Effects on Pulmonary Function, Sputum Clearance, Dyspnea, and Quality of Life

TypeinterventionalSponsorAdnan HashimRan2025 to 2025Enrolled58ConditionsChronic Obstructive Pulmonary Disease (COPD), Airway ClearanceArmsOscillating Positive Expiratory Pressure Therapy, Autogenic Drainage
NCT07664111 nacompletednot on this mapstarted 2026, after this paper: background citation

Effects of an 8-Week Ketogenic Dietary Intervention on Pulmonary Function, Systemic Inflammation, Body Composition, and Functional Exercise Capacity in Men With Mild-to-Moderate Chronic Obstructive Pulmonary Disease: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorAgri Ibrahim Cecen UniversityRan2026 to 2026Enrolled34ConditionsChronic Obstructive Pulmonary Disease (COPD)ArmsKetogenic diet, Standard Dietary Advice
3 · Its place in the literature

Who cites it

814 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,163 citations in OpenAlex.

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754 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Davies AdeloyeCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Peige SongSchool of Public Health and Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yajie ZhuThe George Institute for Global Health, University of Oxford, Oxford, UK.
Harry CampbellCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Aziz SheikhCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Igor RudanCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK. Electronic address: igor.rudan@ed.ac.uk.
NIHR RESPIRE Global Respiratory Health Unit
University of Edinburgh · GBGeorge Institute for Global Health · GBWomen's Hospital, School of Medicine, Zhejiang University · CN

Funding

Medical Research Council MC_PC_19004
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity, disability, and mortality worldwide. We aimed to estimate global, regional, and national COPD prevalence and risk factors to guide policy and population interventions.

methodsFor this systematic review and modelling study, we searched MEDLINE, Embase, Global Health, and CINAHL, for population-based studies on COPD prevalence published between Jan 1, 1990, and Dec 31, 2019. We included data reported using the two main case definitions: the Global Initiative for Chronic Obstructive Lung Disease fixed ratio (GOLD; FEV

findingsWe identified 162 articles reporting population-based studies conducted across 260 sites in 65 countries. In 2019, the global prevalence of COPD among people aged 30-79 years was 10·3% (95% CI 8·2-12·8) using the GOLD case definition, which translates to 391·9 million people (95% CI 312·6-487·9), and 7·6% (5·8-10·1) using the LLN definition, which translates to 292·0 million people (219·8-385·6). Using the GOLD definition, we estimated that 391·9 million (95% CI 312·6-487·9) people aged 30-79 years had COPD worldwide in 2019, with most (315·5 million [246·7-399·6]; 80·5%) living in LMICs. The overall prevalence of GOLD-COPD among people aged 30-79 years was the highest in the Western Pacific region (11·7% [95% CI 9·3-14·6]) and lowest in the region of the Americas (6·8% [95% CI 5·6-8·2]). Globally, male sex (OR 2·1 [95% CI 1·8-2·3]), smoking (current smoker 3·2 [2·5-4·0]; ever smoker 2·3 [2·0-2·5]), body-mass index of less than 18·5 kg/m

interpretationWith more than three-quarters of global COPD cases in LMICs, tackling this chronic condition is a major and increasing challenge for health systems in these settings. In the absence of targeted population-wide efforts and health system reforms in these settings, many of which are under-resourced, achieving a substantial reduction in the burden of COPD globally might remain a difficult task.

fundingNational Institute for Health Research and Health Data Research UK.

Indexed as

Pulmonary Disease, Chronic ObstructiveChronic DiseaseFemaleGlobal HealthHumansMalePrevalenceRisk Factors

Identifiers

PMID35279265
PMCPMC9050565
OpenAlexW4220761888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.