ArticleRadiation oncology (London, England)2022
Dosimetric benefit of MR-guided online adaptive radiotherapy in different tumor entities: liver, lung, abdominal lymph nodes, pancreas and prostate.
Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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49 citing papers in PubMed, 70 citations in OpenAlex.
- Evaluation of inter-fractional anatomical variations due to compression belt placement reproducibility using MR-guided radiotherapy treatment fraction images.Journal of applied clinical medical physics · 2026Article
- MR-Guided Adaptive Radiotherapy in Lung Cancer: Current Landscape and Future Directions.Cancers · 2026Review
- Global hotspots and trends of stereotactic radiotherapy for pancreatic cancer: a bibliometric analysis and visual analysis from 2015 to 2025.Translational cancer research · 2026Article
- MRI-enhanced online adaptive radiotherapy by virtual integration of a standalone MRI simulator and CBCT-based treatment delivery.Radiation oncology (London, England) · 2026Article
- Dosimetric impact of daily MR-guided adaptive radiotherapy across different anatomical sites.Irish journal of medical science · 2026Article
- Nanomaterials reshaping cancer radiotherapy: Radiosensitization mechanisms, delivery and theranostic platforms, multimodal synergy, and clinical translation strategies.Materials today. Bio · 2026Review
- Comparison of gantry-less magnetic resonance guided proton therapy with photon therapy for hepatocellular carcinoma patients.Physics and imaging in radiation oncology · 2026Article
- Impact of tumour proximity to organs-at-risk in adaptive MR-guided SBRT for central lung tumours and metastases.Clinical and translational radiation oncology · 2026Article
- Feasibility of reusing online-generated treatment plans for adaptive radiotherapy in prostate cancer.Physics and imaging in radiation oncology · 2026Article
- Long-term patient experience with online MR-guided radiotherapy: adaptive versus non-adaptive workflow.Frontiers in oncology · 2026Article
- Dosimetric effect of abdominal compression in online adaptive planning for abdominal cancers treated with a 1.5 Tesla magnetic resonance-guided linear accelerator.Physics and imaging in radiation oncology · 2026Article
- Improved PTV coverage and OAR sparing with stereotactic MRI-guided online adaptive radiotherapy with elective fields in pancreatic cancer.Technical innovations & patient support in radiation oncology · 2025Article
- Article
- Adapting to the Future: Introducing the Radiation Oncology Alliance Adaptive Radiotherapy Working Group.Journal of medical imaging and radiation oncology · 2025Article
- Imaging, automation and workflow challenges for online adaptive proton therapy.Physics and imaging in radiation oncology · 2025Article
- Workflow to detect exceeded dose constraints in pancreatic stereotactic body irradiation after intrafraction motion during magnetic resonance-guided adaptive radiotherapy using a deep learning-refined contour propagation tool.Physics and imaging in radiation oncology · 2025Article
- CBCT-based online adaptive radiotherapy of the bladder - geometrical and dosimetrical considerations compared to conventional IGRT.Radiation oncology (London, England) · 2025Article
- Fan beam computed tomography-guided online adaptive external radiotherapy for cervical cancer achieves pathological complete response: A case report.Oncology letters · 2025Article
- Evaluation of model uncertainty in AI-based synthetic CT generation from CBCT for abdominal adaptive radiotherapy.Medical physics · 2025Article
- Assessing treatment accuracy of image-guided liver stereotactic body radiotherapy: a quantitative analysis based on 4D CT through post-therapeutic MRI-morphologic alterations.Quantitative imaging in medicine and surgery · 2025Article
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Authors and funding
12 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHybrid magnetic resonance (MR)-Linac systems have recently been introduced into clinical practice. The systems allow online adaption of the treatment plan with the aim of compensating for interfractional anatomical changes. The aim of this study was to evaluate the dose volume histogram (DVH)-based dosimetric benefits of online adaptive MR-guided radiotherapy (oMRgRT) across different tumor entities and to investigate which subgroup of plans improved the most from adaption.
methodsFifty patients treated with oMRgRT for five different tumor entities (liver, lung, multiple abdominal lymph nodes, pancreas, and prostate) were included in this retrospective analysis. Various target volume (gross tumor volume GTV, clinical target volume CTV, and planning target volume PTV) and organs at risk (OAR) related DVH parameters were compared between the dose distributions before and after plan adaption.
resultsAll subgroups clearly benefited from online plan adaption in terms of improved PTV coverage. For the liver, lung and abdominal lymph nodes cases, a consistent improvement in GTV coverage was found, while many fractions of the prostate subgroup showed acceptable CTV coverage even before plan adaption. The largest median improvements in GTV near-minimum dose (D
conclusionWith online plan adaptation, it was possible to achieve significant improvements in target volume coverage and OAR sparing for various tumor entities and account for interfractional anatomical changes.
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