Evidence map›Paper›PMID 35278531›Full record

ArticleExperimental hematology2022

Ruxolitinib ameliorates progressive anemia and improves survival during episodes of emergency granulopoiesis in Fanconi C

Shirin Hasan, Liping Hu, Olatundun Williams, Elizabeth A Eklund

Open access · hybridAbstract read
In one paragraph

Article in Experimental hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shirin HasanDepartment of Medicine, Northwestern University, Chicago, IL.
Liping HuDepartment of Medicine, Northwestern University, Chicago, IL.
Olatundun WilliamsLurie Children's Hospital, Chicago, IL.
Elizabeth A EklundDepartment of Medicine, Northwestern University, Chicago, IL; Jesse Brown VA Medical Center, Chicago, IL. Electronic address: e-eklund@northwestern.edu.
Northwestern University · USLurie Children's Hospital · US

Funding

Molecular mechanisms for bone marrow failure and clonal progression during the innate immune response in Fanconi AnemiaR01DK121354 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2019 to 2022
$1.4M
Molecular mechanisms of drug resistance and disease progression in acute myeloid leukemia.I01BX004635 · VA · JESSE BROWN VA MEDICAL CENTER · PI EKLUND, ELIZABETH ANN · 2019 to 2025
–
Identifying molecular markers that predict relapse after therapy discontinuation inchronic myeloid leukemia.I01CX001864 · VA · JESSE BROWN VA MEDICAL CENTER · PI Elizabeth Ann Eklund · 2019 to 2026
–
BLRD VA I01 BX004635CSRD VA I01 CX001864NIDDK NIH HHS R01 DK121354
6 · The paper itself

Abstract

Fanconi anemia (FA) is an inherited disorder of DNA repair with hematologic manifestations that range from anemia to bone marrow failure to acute myeloid leukemia. In a murine model of FA (Fancc

Indexed as

ErythropoietinFanconi AnemiaAnimalsFanconi Anemia Complementation Group C ProteinFanconi Anemia Complementation Group ProteinsHematopoiesisMiceMice, KnockoutNitrilesPyrazolesPyrimidinesErythropoietinFanconi Anemia Complementation Group C ProteinFanconi Anemia Complementation Group ProteinsNitrilesPyrazolesPyrimidinesruxolitinib

Identifiers

PMID35278531
PMCPMC9064927
OpenAlexW4221062407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.