Evidence map›Paper›PMID 35278364›Full record

ArticleThe American journal of the medical sciences2022

Self-administered, remote assessment of SARS-CoV-2 seroprevalence in health care workers.

Lauren Card, Christine M Litwin, Scott Curry, Elizabeth H Mack, Paul J Nietert, Eric G Meissner

Open access · greenAbstract read
In one paragraph

Article in The American journal of the medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lauren CardSouth Carolina Clinical & Translational Research Institute, Medical University of South Carolina, Charleston, SC, USA.
Christine M LitwinDepartment of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA.
Scott CurryDepartment of Medicine, Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC, USA.
Elizabeth H MackDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.
Paul J NietertDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
Eric G MeissnerDepartment of Medicine, Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC, USA; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA. Electronic address: meissner@musc.edu.
Medical University of South Carolina · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
The role of SMAD1 and SATB2 in colon patterningP20GM130457 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Hailong Zhang · 2020 to 2026
$18.7M
Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8M
Resource CoreP30AR072582 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAMES C OATES · 2017 to 2026
$8.5M
NCATS NIH HHS UL1 TR001450NIAMS NIH HHS P30 AR072582NIDDK NIH HHS P30 DK123704NIGMS NIH HHS P20 GM130457
6 · The paper itself

Abstract

backgroundOur objective was to safely and remotely assess longitudinal SARS-CoV-2 seroprevalence in at-risk health care workers at the onset of the epidemic.

methodsSelf-administered serologic testing was performed every 30 days up to 5 times using a point-of-care, lateral flow SARS-CoV-2 nucleocapsid IgG immunoassay in a cohort of at-risk health care workers (n = 339) and lower-risk controls (n = 100).

resultsSubjects were enrolled between 4/14/20-5/6/20 and most were clinicians (41%) or nurses (27%). Of 20 subjects who reported confirmed SARS-CoV-2 infection prior to (n = 5, 1%) or during the study (n = 15, 3%), half (10/20) were seropositive. Five additional subjects were seropositive and did not report documented infection. Estimated infection rates in health care workers did not differ from concurrent community rates.

conclusionsThis remotely conducted, contact-free study did not identify serologic evidence of widespread occupational SARS-CoV-2 infection in health care workers.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHealth PersonnelHumansImmunoglobulin GSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin G

Identifiers

PMID35278364
PMCPMC8906004
OpenAlexW4221046115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.