Evidence map›Paper›PMID 35278203›Full record

SynthesisBreast cancer (Tokyo, Japan)2022

Impact of exercise interventions on physical fitness in breast cancer patients and survivors: a systematic review.

Salvatore Ficarra, Ewan Thomas, Antonino Bianco, Ambra Gentile, Petra Thaller, Fulvio Grassadonio, Sofia Papakonstantinou, Thorsten Schulz, Nils Olson, Alexandra Martin and 3 more

2 registry-linked trialsOpen access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Breast cancer (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 79 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 12 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07007039 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Remote Therapeutic Monitoring: Pilot Implementation-Effectiveness Study

TypeinterventionalSponsorShirley Ryan AbilityLabRan2025 to 2027Enrolled25ConditionsCancerArmsDatos Health App
NCT07502963 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer: Randomized Clinical Trial.

TypeinterventionalSponsorUniversity of Vic - Central University of CataloniaRan2026 to 2027Enrolled70ConditionsBreast Cancer, Lung Cancer (Non-Small Cell), Colorectal Cancer, Physical ActivityArmsPREDU Exercise Program, Recommendation Exercise Program
3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 12 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Pooled it
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  3. The effects of aerobic and resistance training across eight cancer types: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  6. The Effects of Post-diagnosis Recreational Aerobic Exercise among Breast Cancer Survivors: A Systematic Review/Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Pooled it
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  15. The impact of multimodal high intensity exercise program comparing online and onsite interventions in breast cancer survivors: a randomized controlled trial.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

Salvatore FicarraSport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy. salvatore.ficarra03@unipa.it.ORCID http://orcid.org/0000-0001-9975-6542
Ewan ThomasSport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Antonino BiancoSport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Ambra GentileSport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.
Petra ThallerOAC-Outdoor Against Cancer, Europe-Wide Outdoor Sport and Exercise Network for Cancer Prevention, Prinzregentenstrasse 97, 81677, Munich, Germany.
Fulvio GrassadonioInternational Centre for the Promotion of Education and Development (CEIPES), Via Francesco Maria Alias 20, 90145, Palermo, Italy.
Sofia PapakonstantinouCreative Thinking Development (CreThiDev), Solonos 8 & Empedokleus, 19009, Ntrafi Rafinas, Attiki, Greece.
Thorsten SchulzDepartment of Sport and Health Sciences, Institute of Preventive Pediatrics, Technical University of Munich, Georg-Brauchle-Ring 60/62, D-80992, Munich, Germany.
Nils OlsonDepartment of Sport and Health Sciences, Institute of Preventive Pediatrics, Technical University of Munich, Georg-Brauchle-Ring 60/62, D-80992, Munich, Germany.
Alexandra MartinDepartment of Sport and Health Sciences, Technical University of Munich, Uptown Munich-Campus D Georg-Brauchle-Ring 60/62, D-80992, Munich, Germany.
Christian WagnerNaturfreunde, Bundesorganisation, Viktoriagasse 6, 1150, Vienna, Austria.
Anna NordströmDepartment of Public Health and Clinical Medicine, Section of Sustainable Health, Umeå University, Umeå, Sweden.
Hande HofmannDepartment of Sport and Health Sciences, Institute of Preventive Pediatrics, Technical University of Munich, Georg-Brauchle-Ring 60/62, D-80992, Munich, Germany.
Technical University of Munich · DEUniversity of Palermo · ITCreative Systems Engineering (Greece) · GRGeological Survey of Austria · ATNational Centre for Disease Prevention and Control · ITUmeå University · SE

Funding

"OaC (Outdoor against Cancer): my goal" Project, founded by the ERASMUS+ Programme of the European Commission 603021-EPP-1-2018-1-DE-SPO-SCP
6 · The paper itself

Abstract

backgroundThis systematic review aims to identify the effects of exercise interventions in patients with breast cancer (BCP) and survivors (BCS) on selected variables of physical fitness.

methodsA comprehensive literature search was conducted using Medline and Scopus. Randomized controlled trials with isolated exercise interventions in BCP and BCS women (< 5 years from therapy completion) were included. The risk of bias (RoB) assessment was conducted using the Cochrane RoB-2-tool. Variables regarding cardiorespiratory fitness (CRF), strength (ST), fatigue (F) and health-related quality of life (HRQoL) were discussed.

resultsOf the 336 studies initially identified, 22 met all the inclusion criteria and were deemed eligible. RoB assessment indicated that the studies had predominantly "some concerns" or had "low RoB", with only 3 studies presenting a "high RoB". The mean duration and frequency of exercise interventions were 19 weeks and 3 sessions/week, performed at moderate intensity (65% VO

conclusionsExercise interventions seem to be a valuable strategy in BCP to avoid the decline of CRF, ST, F and HRQoL. Conversely, improved physical function among BCS is observed for the same variables. Resistance training and combined interventions seem to provide the most encouraging variations of the selected outcomes. PROSPERO REGISTRATION ID: CRD42021237917.

Indexed as

Breast NeoplasmsResistance TrainingExerciseExercise TherapyFemaleHumansPhysical FitnessQuality of LifeSurvivorsBreast neoplasmFatiguePhysical activityQuality of lifeStrength

Identifiers

PMID35278203
PMCPMC9021138
OpenAlexW4220727337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.