Evidence map›Paper›PMID 35278121›Full record

ArticleEuropean radiology2022

Soft tissue sarcoma: IVIM and DKI parameters correlate with Ki-67 labeling index on direct comparison of MRI and histopathological slices.

Kai Zhang, Yue Dai, Yajie Liu, Juan Tao, Ziang Pan, Lizhi Xie, Shaowu Wang

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. DKI andBMC medical imaging · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kai Zhang *Department of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China.
Yue Dai *Department of Radiology, Dalian Municipal Central Hospital, Dalian, China.
Yajie LiuDepartment of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China.
Juan TaoDepartment of Pathology, The Second Hospital, Dalian Medical University, Dalian, China.
Ziang PanDepartment of Pathology, The Second Hospital, Dalian Medical University, Dalian, China.
Lizhi XieGE Healthcare, MR Research China, Beijing, China.
Shaowu WangDepartment of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China. wsw_2018@163.com.ORCID http://orcid.org/0000-0002-2221-1154
Dalian Medical University · CNDalian Municipal Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the correlation of parameters derived from intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) with Ki-67 labeling index (LI) in soft tissue sarcoma (STS).

methodsForty-one patients with STS underwent IVIM and DKI imaging at 3.0 MRI. The standard apparent diffusion coefficient (ADC), true diffusion coefficient (D), pseudo-diffusion coefficient (D

resultsThe high-expression group displayed lower standard ADC, D, and MD values and a higher MK value than the low-expression group. No significant differences were found for D

conclusionsIVIM and DKI parameters are correlated with Ki-67 LI. MK may be the optimal imaging biomarker for assessing the Ki-67 expression of STS. KEY POINTS: • IVIM and DKI parameters are correlated with the expression of Ki-67 in STS. • The MRI-pathology control method ensured a strong correlation between MRI slices and histologic sections, resulting in a robust radiological-pathological correlation.

Indexed as

SarcomaSoft Tissue NeoplasmsDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansKi-67 AntigenMagnetic Resonance ImagingKi-67 AntigenDiffusion magnetic resonance imagingKi-67 antigenSarcoma

Identifiers

PMID35278121
OpenAlexW4221120801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.