Evidence map›Paper›PMID 35277987›Full record

SynthesisContact dermatitis2022

Lifestyle factors and hand eczema: A systematic review and meta-analysis of observational studies.

Laura Loman, Marjolein J Brands, Anna A L Massella Patsea, Klaziena Politiek, Bernd W M Arents, Marie L A Schuttelaar

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Contact dermatitis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Chronic Hand Eczema (CHE): A Narrative Review.Dermatology and therapy · 2025
    Review
  9. Chronic Hand Eczema.American journal of clinical dermatology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Are There Ethnic Differences in Hand Eczema? A Review.Journal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura LomanDepartment of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-2731-9284
Marjolein J BrandsDepartment of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-2251-6596
Anna A L Massella PatseaDepartment of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-6994-809X
Klaziena PolitiekDepartment of Dermatology, Medical Center Leeuwarden, Leeuwarden, The Netherlands.ORCID https://orcid.org/0000-0001-6475-6876
Bernd W M ArentsDutch Association for People with Atopic Dermatitis, Nijkerk, The Netherlands.ORCID https://orcid.org/0000-0001-6884-8014
Marie L A SchuttelaarDepartment of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-0766-4382

Funding

University Medical Center Groningen
6 · The paper itself

Abstract

Evidence regarding the association between lifestyle factors and hand eczema is limited.To extensively investigate the association between lifestyle factors (smoking, alcohol consumption, stress, physical activity, body mass index, diet, and sleep) and the prevalence, incidence, subtype, severity, and prognosis of hand eczema, a systematic review and meta-analysis were conducted in accordance with the Meta-analysis Of Observational Studies in Epidemiology consensus statement. MEDLINE, Embase, and Web of Science were searched up to October 2021. The (modified) Newcastle-Ottawa Scale was used to judge risk of bias. Quality of the evidence was rated using the Grades of Recommendation, Assessment, Development and Evaluation approach. Eligibility and quality were blindly assessed by two independent investigators; disagreements were resolved by a third investigator. Data were pooled using a random-effects model, and when insufficient for a meta-analysis, evidence was narratively summarized. Fifty-five studies were included. The meta-analysis (17 studies) found very low quality evidence that smoking is associated with a higher prevalence of hand eczema (odds ratio 1.18, 95% confidence interval 1.09-1.26). No convincing evidence of associations for the other lifestyle factors with hand eczema were found, mostly due to heterogeneity, conflicting results, and/or the limited number of studies per outcome.

Indexed as

Dermatitis, Allergic ContactEczemaHumansLife StyleObservational Studies as TopicOdds RatioSmokingalcohol consumptionBMIhand dermatitishand eczemalifestylephysical activitysmokingstress

Identifiers

PMID35277987
PMCPMC9541324

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.