ArticleHeredity2022
Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard.
Article in Heredity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Genotype-Phenotype-Environment Associations and Potential Local Adaptation Signals in the Mesquite Lizard Along the Eastern Trans-Mexican Volcanic Belt.Molecular ecology · 2026Article
- Population Genomic Structure of Sorghum Landraces Across Landscape, Environment and Culture.Molecular ecology · 2026Article
- Surviving the Squeeze: Genomic Analysis of a Successful Invasion by European Common Wall Lizards (Podarcis muralis) in North America (Ohio, USA).Molecular ecology · 2026Article
- Detecting local adaptation under weak genetic structure in an endemic damselfly: an integrative eco-evolutionary approach.BMC ecology and evolution · 2026Article
- Population genomic structure of sorghum landraces across landscape, environment and culture.bioRxiv : the preprint server for biology · 2025Article
- Climate and Socio-Sexual Environment Predict Interpopulation Variation in Chemical Signaling Glands in a Widespread Lizard.Integrative zoology · 2025Article
- Range-wide climate risk and adaptive potential in a cold-water fish species.Nature communications · 2025Article
- Functional connectivity patterns of the Giant Toad Rhinella horribilis in anthropogenically modified landscapes.PloS one · 2025Article
- Genetic admixture drives climate adaptation in the bank vole.Communications biology · 2024Article
- Adaptive introgression reveals the genetic basis of a sexually selected syndrome in wall lizards.Science advances · 2024Article
- Habitat-associated Genomic Variation in a Wall Lizard from an Oceanic Island.Genome biology and evolution · 2023Article
- Unravelling the origin of the common wall lizards (Biodiversity data journal · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Species distributed across climatic gradients will typically experience spatial variation in selection, but gene flow can prevent such selection from causing population genetic differentiation and local adaptation. Here, we studied genomic variation of 415 individuals across 34 populations of the common wall lizard (Podarcis muralis) in central Italy. This species is highly abundant throughout this region and populations belong to a single genetic lineage, yet there is extensive phenotypic variation across climatic regimes. We used redundancy analysis to, first, quantify the effect of climate and geography on population genomic variation in this region and, second, to test if climate consistently sorts specific alleles across the landscape. Climate explained 5% of the population genomic variation across the landscape, about half of which was collinear with geography. Linear models and redundancy analyses identified loci that were significantly differentiated across climatic regimes. These loci were distributed across the genome and physically associated with genes putatively involved in thermal tolerance, regulation of temperature-dependent metabolism and reproductive activity, and body colouration. Together, these findings suggest that climate can exercise sufficient selection in lizards to promote genetic differentiation across the landscape in spite of high gene flow.
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