ArticleScientific reports2022
Mild chronic exposure to pesticides alters physiological markers of honey bee health without perturbing the core gut microbiota.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- A network-based meta-analysis of the honeybee gut microbiome: geographic, seasonal, and pesticide-associated shifts.Scientific reports · 2026Pooled it
- Protective effects of rosmarinic acid against carbaryl-exposed toxicity in honey bees (Apis mellifera): histopathological and molecular docking evidence.Veterinary research communications · 2026Article
- Sublethal Acetamiprid Exposure Induces Ovarian Degeneration and HSP70/HSP90 Overexpression in Honey Bee Queens (Veterinary sciences · 2026Article
- Disruption of Antioxidant Defense Systems in Honey Bees and Wild Bees Under Environmental Xenobiotic Pressure.Antioxidants (Basel, Switzerland) · 2026Review
- Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology.Proteomics · 2026Article
- Article
- Glyphosate-Based Herbicides and Their Potential Impact on the Microbiota of Social Bees.Toxics · 2025Review
- Changes in the Activities of Antioxidant Enzymes in the Fat Body and Hemolymph ofAntioxidants (Basel, Switzerland) · 2025Article
- Article
- Cyto and Genoprotective Potential of Tannic Acid Against Cadmium and Nickel Co-exposure Induced Hepato-Renal Toxicity in BALB/c Mice.Biological trace element research · 2024Article
- Glyphosate effects on growth and biofilm formation in bee gut symbionts and diverse associated bacteria.Applied and environmental microbiology · 2024Article
- Prospects of probiotics in beekeeping: a review for sustainable approach to boost honeybee health.Archives of microbiology · 2024Review
- The honeybee microbiota and its impact on health and disease.Nature reviews. Microbiology · 2024Review
- Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages.mSystems · 2024Article
- Phytochemicals, Probiotics, Recombinant Proteins: Enzymatic Remedies to Pesticide Poisonings in Bees.Environmental science & technology · 2024Review
- Impact of glyphosate (RoundupGut microbes · 2023Review
- The Bacterial GJournal of chemical ecology · 2023Article
- Low Levels of Hive Stress Are Associated with Decreased Honey Activity and Changes to the Gut Microbiome of Resident Honey Bees.Microbiology spectrum · 2023Article
- The effects of glyphosate, pure or in herbicide formulation, on bumble bees and their gut microbial communities.The Science of the total environment · 2023Article
- Effect of Chronic Exposure to Sublethal Doses of Imidacloprid and Nosema ceranae on Immunity, Gut Microbiota, and Survival of Africanized Honey Bees.Microbial ecology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies highlighted that exposure to glyphosate can affect specific members of the core gut microbiota of honey bee workers. However, in this study, bees were exposed to relatively high glyphosate concentrations. Here, we chronically exposed newly emerged honey bees to imidacloprid, glyphosate and difenoconazole, individually and in a ternary mixture, at an environmental concentration of 0.1 µg/L. We studied the effects of these exposures on the establishment of the gut microbiota, the physiological status, the longevity, and food consumption of the host. The core bacterial species were not affected by the exposure to the three pesticides. Negative effects were observed but they were restricted to few transient non-core bacterial species. However, in the absence of the core microbiota, the pesticides induced physiological disruption by directly altering the detoxification system, the antioxidant defenses, and the metabolism of the host. Our study indicates that even mild exposure to pesticides can directly alter the physiological homeostasis of newly emerged honey bees and particularly if the individuals exhibit a dysbiosis (i.e. mostly lack the core microbiota). This highlights the importance of an early establishment of a healthy gut bacterial community to strengthen the natural defenses of the honey bee against xenobiotic stressors.
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