ArticleInternational dental journal2022
Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome.
Article in International dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Comparison of oral health indices and parental awareness in children with and without idiopathic nephrotic syndrome. A case-control study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Pulp calcification and pulp canal obliteration: from biological mechanisms to contemporary clinical management and digital navigation.The Saudi dental journal · 2026Review
- Developmental defects of enamel in children with nephrotic syndrome: a cross-sectional study of proportion and independently associated factors.Pediatric nephrology (Berlin, Germany) · 2026Article
- Developmental Disturbances of Teeth in Children with Autism Spectrum Disorder and Attention-deficit Hyperactivity Disorder: A Cross-sectional Study.International journal of clinical pediatric dentistry · 2025Article
- Long-Term Impact of Interdisciplinary Collaboration on Oral Health in Children with Nephrotic Syndrome: A 12-Year Retrospective Study.Journal of clinical medicine · 2025Article
- Salivary Interleukin-6 and Interleukin-18 Levels and Their Association with Dental Health in Children with Idiopathic Nephrotic Syndrome.International journal of molecular sciences · 2025Article
- A Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage.Children (Basel, Switzerland) · 2025Article
- The Potential Impact of MYH9 (rs3752462) and ELMO1 (rs741301) Genetic Variants on the Risk of Nephrotic Syndrome Incidence.Biochemical genetics · 2024Article
- Is there an association between molar incisor hypomineralization and developmental dental anomalies? A case-control study.BMC oral health · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTreatment with glucocorticoids in children with nephrotic syndrome can be the cause of developmental disorders of the masticatory organ and bone or teeth abnormalities. The aim was to assess the frequency and type of dental abnormalities and the correlation of their occurrence with a dosage of glucocorticoids and treatment time in children with idiopathic nephrotic syndrome.
methodsThe study group consisted of 31 patients aged 5 to 17 diagnosed with idiopathic steroid-sensitive nephrotic syndrome and 33 overall healthy children. The studies included clinical evaluation of dentition, radiologic diagnostics, and statistical analysis.
resultsIn the study group, 77.4% of patients were diagnosed with abnormalities in dental development. Tooth number disorders, presence of persistent deciduous teeth and impacted teeth, abnormal crown or root shape, developmental defects of enamel, pulp stones, and bone structure disorders were identified. Statistical analysis showed significant differences in the average treatment time of glucocorticoids in patients without and with tooth developmental abnormalities.
conclusionsLong-term use of glucocorticoids in children with nephrotic syndrome promotes the occurrence of developmental abnormalities of the teeth, calcification of the pulp, and disorders of bone tissue metabolism. For this reason, patients with steroid-sensitive nephrotic syndrome should be under the constant care of a dentist.
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