ArticleCardiovascular diabetology2022
Association between triglyceride glucose index and carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China.
Article in Cardiovascular diabetology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 72 citations in OpenAlex.
- Relationship between the circulating N-terminal pro B-type natriuretic peptide and the risk of carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a CSCD-TCMCardiovascular diabetology · 2023Trial
- Correlation of Cardiometabolic Index With Premature Coronary Heart Disease and Coronary Artery Disease Severity in Menopausal Women.Reviews in cardiovascular medicine · 2026Article
- Association of triglyceride-glucose index with carotid atherosclerosis in the general population: a case-control study of 14,535 participants.BMC cardiovascular disorders · 2026Article
- Prognostic effect of triglyceride glucose-related parameters on all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome: evidence from international multi-cohort studies.Cardiovascular diabetology · 2026Article
- Association Between the Triglyceride-Glucose Index and Incident Chronic Severe Pain in Middle-Aged and Older Chinese Adults: A Nationwide Cohort Study.Pain research & management · 2026Article
- TyG-ABSI as a novel metabolic obesity indicator for carotid plaque: an explainable machine learning study using SHAP in low-income population.BMC endocrine disorders · 2025Article
- Article
- The triglyceride-glucose index and acute kidney injury risk in critically ill patients with coronary artery disease.Renal failure · 2025Article
- Development and validation of a machine learning model for predicting vulnerable carotid plaques using routine blood biomarkers and derived indicators: insights into sex-related risk patterns.Cardiovascular diabetology · 2025Article
- Triglyceride-glucose index combined with body roundness index predicts cardiovascular risk in middle-aged and elderly individuals: a 10-year cohort study.Scientific reports · 2025Article
- Linking Triglyceride-Glucose Index to Spontaneous Intracerebral Hemorrhage: Mechanisms and Predictive Insights.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Observational
- Associations of the triglyceride-glucose index and remnant cholesterol levels with the prevalence of Carotid Plaque in patients with type 2 diabetes: a retrospective study.Lipids in health and disease · 2025Article
- Associations of healthy lifestyle and family income to poverty ratio with all-cause mortality among people with prediabetes and diabetes: a prospective cohort study.BMC public health · 2025Article
- The Impact of Triglyceride-Glucose Index on Carotid Atherosclerosis: A Prospective Cohort Study in Middle Aged and Elderly Low-Income in Rural Chinese.Risk management and healthcare policy · 2025Article
- The metabolic syndrome-insulin resistance index: a tool for identifying dyslipidemia across varied glucose metabolic score in patients with cardiovascular disease.Frontiers in endocrinology · 2025Article
- Impaired sensitivity to thyroid hormones is associated with ASCVD risk factors in Beijing in euthyroid population: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Prognostic Value of Triglyceride Glucose Index in ST-Elevation Myocardial Infarction: A Key Predictor of Mortality and Thrombus Burden.Diagnostics (Basel, Switzerland) · 2024Article
- Epidemiology and current management of cardiovascular disease in China.Journal of geriatric cardiology : JGC · 2024Article
- Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study.Frontiers in endocrinology · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe triglyceride glucose (TyG) index serves as a surrogate indicator of insulin resistance. However, there is limited evidence on the association between the TyG index and carotid artery plaque (CAP) in patients with coronary heart disease (CHD).
methodsThe 10,535 CHD patients were divided according to TyG index quartiles (Q1: TyG index < 8.52; Q2: 8.52 ≤ TyG index < 8.93; Q3: 8.93 ≤ TyG index ≤ 9.40; Q4: TyG index > 9.40). The presence or absence of CAP was determined by carotid ultrasonography. Logistic regression was used to analyze the relationship between the TyG index and CAP in CHD patients. The relationship between the TyG index and CAP in according to sex, age groups, and glucose metabolism states were also assessed.
resultsThe baseline analysis showed that there were significant differences in related parameters among CHD patients divided into four groups according to the quartile of the TyG index. In the multi-adjusted modles, compared to Q1 of the TyG index, the odds ratios (OR) for Q4 of the TyG index for CAP were 1.37 (95% confidence interval [CI] 1.28-1.47) in CHD patients. The association between the TyG index and CAP in female (OR: 1.35; 95% CI 1.29-1.43) was higher than that in male (OR: 1.20; 95% CI 1.13-1.27). The OR value of middle-aged (≤ 60 years old) patients (OR: 1.34; 95% CI 1.26-1.42) was higher than that in elderly (> 60 years old) patients (OR: 1.16; 95% CI 1.11-1.22). In different glucose metabolism states, the TyG index of CHD patients was significantly related to the risk of CAP, with the highest OR value observed for diabetes (OR: 1.36; 95% CI 1.26-1.46).
conclusionsThe TyG index and CAP showed a significant association in CHD patients. This association between TyG index and CAP in CHD patients is higher in female than in male, and the association in middle-aged and elderly patients is higher than that in elderly patients. In the condition of DM, the association between TyG index and carotid artery plaque in CHD patients is higher.
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