Evidence map›Paper›PMID 35277041›Full record

ArticleNutrients2022

Distribution and Determinants of Serum Zinc, Copper, and Selenium Levels among Children under Five Years from Popokabaka, Democratic Republic of Congo: A Cross-Sectional Study.

Branly Kilola Mbunga, Ingunn M S Engebretsen, Tor A Strand, Elin L F Gjengdal, Pierre Z Akilimali, Mina M Langfjord, Pierrot L Tugirimana, Mala Ali Mapatano

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Branly Kilola MbungaKinshasa School of Public Health, University of Kinshasa, Kinshasa, Congo.ORCID 0000-0003-2380-0484
Ingunn M S EngebretsenDepartment of Global Public Health and Primary Care, Centre for International Health, University of Bergen, 5009 Bergen, Norway.ORCID 0000-0001-5852-3611
Tor A StrandDepartment of Global Public Health and Primary Care, Centre for International Health, University of Bergen, 5009 Bergen, Norway.
Elin L F GjengdalFaculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences, 1432 Ås, Norway.ORCID 0000-0002-7771-0153
Pierre Z AkilimaliKinshasa School of Public Health, University of Kinshasa, Kinshasa, Congo.ORCID 0000-0002-3828-6214
Mina M LangfjordFaculty of Environmental Sciences and Natural Resource Management, Norwegian University of Life Sciences, 1432 Ås, Norway.
Pierrot L TugirimanaFaculty of Medicine, University of Goma, Goma, Congo.ORCID 0000-0002-1904-4885
Mala Ali MapatanoKinshasa School of Public Health, University of Kinshasa, Kinshasa, Congo.
University of Kinshasa · CDNorwegian University of Life Sciences · NOUniversity of Bergen · NOUniversity of Goma · CD

Funding

NORAD GrowNut Project: QZA-0484, COG-13/0002
6 · The paper itself

Abstract

Information about essential trace elements among children in many African countries, including the Democratic Republic of Congo (DRC), is limited. We aimed to measure the distribution and determinants of serum zinc (Zn), copper (Cu), and selenium (Se) concentrations in a representative sample of children under five years old. We conducted a community-based cross-sectional study in Popokabaka, DRC. Blood samples were drawn from 412 children. The serum concentrations of minerals were measured using inductively coupled plasma−mass spectrometry. The median concentrations (P25−P75) of Zn, Cu, and Se were 61.9 µg/dL (52.8−70.2), 145.5 (120.0−167.0) µg/dL and 5.3 (4.3−6.3) µg/dL. The CRP-adjusted prevalence of serum Se deficiency was 84.1% (95% confidence interval [CI] 81.4−87.0) and of Zn deficiency was 64.6% (95% CI 59.8−69.1%). Only a few children were Cu deficient [1.5% (0.6−3.2)]. Evidence of inflammation (C-reactive protein, >5 mg/L) was associated with a lower Se concentration and higher Cu concentration. Furthermore, serum Se concentration was positively associated with linear growth. The average Cu/Zn molar ratio (2:1) was twice that recommended. Children in western Popokabaka had higher Zn and Se levels than their eastern neighbors. Zinc and selenium deficiencies are common among children in Popokabaka and require attention and prioritization.

Indexed as

CopperSeleniumChildChild, PreschoolCross-Sectional StudiesDemocratic Republic of the CongoHumansZincCopperSeleniumZincchildrencopperdeficiencyPopokabakaseleniumzinc

Identifiers

PMID35277041
PMCPMC8839910
OpenAlexW4210539605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.