Trial reportNutrients2022
Continuous versus Intermittent Enteral Tube Feeding for Critically Ill Patients: A Prospective, Randomized Controlled Trial.
Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Intermittent versus continuous enteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2026Pooled it
- Effects of continuous versus intermittent enteral feeding on feeding tolerance in critically ill adults: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Risk factors for enteral feeding intolerance in critically ill patients: an updated systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Strategies to Maximize the Benefits of Evidence-Based Enteral Nutrition: A Narrative Review.Nutrients · 2025Pooled it
- Intermittent enteral nutrition may increase gastrointestinal complications and mortality in critically ill patients.Frontiers in nutrition · 2025Pooled it
- Clinical efficacy of enteral nutrition feeding modalities in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.European journal of clinical nutrition · 2023Pooled it
- Continuous versus Intermittent Enteral Feeding in Critically Ill Children: A Systematic Review.Nutrients · 2023Pooled it
- Impact of a Staged Enteral Nutrition Nursing Pathway Based on Dynamic Assessment of Tolerance and Aspiration Risk vs Usual Care on Feeding Intolerance in Older Adult Patients With Acute Ischemic Stroke and Dysphagia: A Single-Center Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026Trial
- Which is better for glycemic control? bolus, intermittent (nocturnal pause) or continuous enteral feeding in septic critically ill patients.Science progressTrial
- Intermittent vs. continuous: a comparative narrative review of enteral and parenteral nutrition support strategies in the perioperative setting.European journal of clinical nutrition · 2026Review
- Comparison of nasogastric tube and intermittent oro-esophageal tube feeding in patients with dysphagia and evaluation of an assessment scale for initial nutritional support selection.Frontiers in nutrition · 2026Article
- Constipation in critically ill adults.World journal of gastrointestinal pathophysiology · 2025Review
- From Ancient Enemas to Tube Feeding, I: History, Administration, and Nutritional Composition of Commercial Versus Food-Based Formulas in Critical Illness.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2025Review
- Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- The Japanese Critical Care Nutrition Guideline 2024.Journal of intensive care · 2025Review
- An Assessment of Intermittent and Continuous Enteral Feeding in Critically Ill Children.Nutrients · 2025Observational
- Enteral Nutrition Practices and Complications in ICU Settings: A Cross-Sectional Study of Healthcare Professionals' Perspectives in Saudi Arabia.Journal of multidisciplinary healthcare · 2025Article
- Article
- Bolus Versus Continuous Enteral Feeding for Critically Ill Patients: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Qualitative study on the ability of neurological nurses to manage patients with indwelling gastrointestinal canal.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The appropriate strategy for enteral feeding remains a matter of debate. We hypothesized that continuous enteral feeding would result in higher rates of achieving target nutrition during the first 7 days compared with intermittent enteral feeding. We conducted an unblinded, single-center, parallel-group, randomized controlled trial involving adult patients admitted to the medical intensive care unit who required mechanical ventilation to determine the efficacy and safety of continuous enteral feeding for critically ill patients compared with intermittent enteral feeding. The primary endpoint was the achievement of ≥80% of the target nutrition requirement during the first 7 days after starting enteral feeding. A total of 99 patients were included in the modified intention-to-treat analysis (intermittent enteral feeding group,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.