ReviewNutrients2022
The Role of Minerals in the Optimal Functioning of the Immune System.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
139 citing papers in PubMed, 300 citations in OpenAlex.
- Consumption of lettuce with seaweed extract biostimulant application improved iron homeostasis in a randomized interventional trial of healthy individuals.Scientific reports · 2025Trial
- Sodium Selenite Preconditioning Reprograms Mesenchymal Stem Cell Behavior Under Inflammatory Stress to Enhance Anti-Inflammatory Macrophage Responses.Biological trace element research · 2026Article
- Natural Mineral Water (Hora) Supplementation Improves Growth Performance and Carcass Characteristics of Sheep in Ethiopia.Veterinary medicine and science · 2026Article
- Hyposaline LUSO Mineral Water Drives Murine Macrophage Polarization Towards an Anti-Inflammatory M2 Phenotype.Food science & nutrition · 2026Article
- Nutritional profiling, bioactive phytochemicals, and functional food components of wild edible fruits from the Indo-Burma biodiversity hotspot.Scientific reports · 2026Article
- Serum Zinc Threshold and the Prognostic Impact of Zinc Supplementation in Liver Cirrhosis.Nutrients · 2026Article
- Associations of metals and micronutrients with functional disability in Chinese older adults: a mixture analysis approach.Scientific reports · 2026Article
- Valorization of By-Products for Functional Ingredients in Meat and Meat Replacers: A Circular Bioeconomy Approach.Foods (Basel, Switzerland) · 2026Review
- Mechanisms, Modulation, and Mitigation: Dietary-Gut Microbiome Strategies Against Antibiotic Resistance.Probiotics and antimicrobial proteins · 2026Review
- Influence of Free and Microencapsulated Extracts from Onion Peels on the Performance of Fortified Fresh Cheese.Foods (Basel, Switzerland) · 2026Article
- Valorization of By-Products from White Cabbage (Foods (Basel, Switzerland) · 2026Article
- Trace Elements and Viral Infectious Diseases: Dual Roles in Pathogenesis and Immunity.Infectious disease reports · 2026Review
- LC-QTOF-MS/MS for tentative identification of antioxidant peptides in defatted Spirulina platensis cakes obtained by supercritical COAnalytical and bioanalytical chemistry · 2026Article
- Comparison of Mineral Levels in Blood and Hair Samples of Healthy Adults: Evaluating the Clinical Utility of Hair Mineral Analysis.Biological trace element research · 2026Article
- Polyphenolic and Mineral Composition of Functional Foods Based on Rape Honey and Dried Fruits.Molecules (Basel, Switzerland) · 2026Article
- Association between multiple urinary metals and visceral obesity: a large cross-sectional study in South China.European journal of medical research · 2026Article
- ASAS-NANP symposium: mathematical modeling in animal nutrition: agent‑based modeling of nutrient requirements and growth performance in growing-finishing pigs for sustainable production systems.Journal of animal science · 2026Article
- Energy potential, health benefits, antinutrient reduction methods, and nutritional properties of Indian millets: a review.Frontiers in nutrition · 2026Review
- Impact of State of Ripeness and Culinary Treatments on the Hypoglycemic, Antioxidant, and Nutritional Properties of Two Varieties ofInternational journal of food science · 2026Article
- Inflammation and Chronic Disease: The Mediterranean Diet in Precision and Personalized Nutrition.Annals of nutrition & metabolism · 2026Review
79 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minerals fulfil a wide variety of functions in the optimal functioning of the immune system. This review reports on the minerals that are essential for the immune system's function and inflammation regulation. We also discuss nutritional aspects of optimized mineral supply. The supply of minerals is important for the optimal function of the innate immune system as well as for components of adaptive immune defense; this involves defense mechanisms against pathogens in addition to the long-term balance of pro- and anti-inflammatory regulation. Generally, a balanced diet is sufficient to supply the required balance of minerals to help support the immune system. Although a mineral deficiency is rare, there are nevertheless at-risk groups who should pay attention to ensure they are receiving a sufficient supply of minerals such as magnesium, zinc, copper, iron, and selenium. A deficiency in any of these minerals could temporarily reduce immune competence, or even disrupt systemic inflammation regulation in the long term. Therefore, knowledge of the mechanisms and supply of these minerals is important. In exceptional cases, a deficiency should be compensated by supplementation; however, supplement over-consumption may be negative to the immune system, and should be avoided. Accordingly, any supplementation should be medically clarified and should only be administered in prescribed concentrations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.